- <![CDATA[[Boai] IVIS Lumina S5 Imaging System]]><![CDATA[<div class="ed_model05 clearfix">
<div class="ed_pic_right"><img alt="IVIS Lumina S5 Imaging System" src="/userfiles/orden/images/20250331103400940.jpg" /></div>
<ul>
<li class="ed_txt"><strong>IVIS Lumina S5 Imaging System</strong>
<ul>
<li class="ed_txt">Model: Revvity IVIS Lumina S5</li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument expert: </strong>
<ul>
<li class="ed_txt"><strong>Prof. Chao, Jui-I</strong>
<ul>
<li class="ed_txt">Extension 56965</li>
</ul>
</li>
<li class="ed_txt"><strong>Prof. Chao, Chi-Hong</strong>
<ul>
<li class="ed_txt">Extension 59725</li>
</ul>
</li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument Operation Technician: Wang, Cing-Hong</strong><strong> [full time]</strong>
<ul>
<li class="ed_txt">Extension 56939</li>
<li class="ed_txt">E-mail <a href="mailto:mailto:chwang.bt10@nycu.edu.tw" title="chwang.bt10@nycu.edu.tw">chwang.bt10@nycu.edu.tw</a></li>
</ul>
</li>
<li class="ed_txt"><strong>Contact Person: Ms. Chen, I-Jing</strong>
<ul>
<li class="ed_txt">Extension 56941</li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument Location</strong>: Animal Center Room202, Boai Campus</li>
</ul>
<div class="ed_txt"> </div>
</div>]]>Instrumentation Resource Center 2026-02-03Introduction<div class="ed_model01 clearfix">
<div class="ed_txt"><strong><span style="font-size:120%;">IVIS Lumina S5 Imaging System</span></strong><br />
<strong>Instrument brand, model, year of purchase</strong></div>
<ul>
<li class="ed_txt">Brand: Revvity</li>
<li class="ed_txt">Model: IVIS Lumina S5</li>
<li class="ed_txt">Purchase date: November, 2024</li>
</ul>
<div class="ed_txt"><strong>Important Specifications</strong></div>
<ul>
<li class="ed_txt">IVIS Lumina S5 Imaging System</li>
<li class="ed_txt">PerkinElmer RAS-4 Rodent Anesthesia System</li>
<li class="ed_txt">Resolution 2048×2048</li>
<li class="ed_txt">Detection range 410nm-790nm (can be applied to various luminescence/fluorescent imaging)</li>
<li class="ed_txt">Field size 2.7x2.7 cm</li>
<li class="ed_txt">Heated lifting photography platform for small animals</li>
<li class="ed_txt">Fluorescent light source</li>
<li class="ed_txt">Fluorescence detection filter</li>
<li class="ed_txt">Excitation: 410-790 nm</li>
<li class="ed_txt">Emission: 500-865 nm</li>
</ul>
</div>Services and Opening Hours<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>Services</strong></div>
<ol>
<li class="ed_txt">Absolute quantitative analysis and measurement of luminescence for living animals and plants</li>
<li class="ed_txt">Absolute quantitative analysis and measurement of fluorescence for living animals and plants</li>
<li class="ed_txt">Absolute quantitative analysis and measurement of luminescence cell lines</li>
<li class="ed_txt">Absolute quantitative analysis and measurement of luminescent strains</li>
<li class="ed_txt">Absolute quantitative analysis and measurement of fluorescent cell lines.</li>
<li class="ed_txt">Absolute quantitative analysis and measurement of fluorescent strains.</li>
<li class="ed_txt">Three-dimensional image reconstruction and signal depth detection </li>
<li class="ed_txt">Mouse animal organ model set and signal position analysis </li>
<li class="ed_txt">3D image output </li>
<li class="ed_txt">Multi-fluorescence analysis and automatic background subtraction </li>
</ol>
<div class="ed_txt">
<div class="ed_model19 clearfix"><strong>Opening Hours</strong></div>
<ol>
<li class="ed_model19 clearfix">Monday to Thursday: 9:00 – 17:00</li>
<li class="ed_model19 clearfix">Friday: 9:00 – 1200</li>
</ol>
</div>
</div>System Open Level<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>System Open Level</strong></div>
<ol>
<li class="ed_txt">General working hours: Level B、Level D</li>
<li class="ed_txt">Night and holiday periods: Level C</li>
</ol>
<div class="ed_txt"><strong><u>System Level Description</u></strong></div>
<ul>
<li class="ed_txt">Level A: Open to students who need to use it. They can operate it independently after training and assessment.</li>
<li class="ed_txt">Level B: Each professor nominates one student for training, while the rest operate under those who have been trained. Professors with multiple students using the instrument can request an increase in the number of students receiving training.</li>
<li class="ed_txt">Level C: The instrument administrator selects several students recommended by the professor to receive training. After passing the assessment, they can operate the instrument independently and be responsible for the delegated operation service.</li>
<li class="ed_txt">Level D: The technical personnel of this machine shall accept commissioned services.</li>
</ul>
</div>Charges<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>Charging standards</strong></div>
<ul>
<li class="ed_txt">On-campus: NT$1,200/hour (please prepare your own Isoflurane)</li>
<li class="ed_txt">Off-campus: NT$3,000/hour (please prepare your own Isoflurane)</li>
<li class="ed_txt">Commission Service Fee: NT$4,500 per hour</li>
</ul>
<div class="ed_txt">Note:</div>
<ol>
<li class="ed_txt">Billing commences upon software login and CCD cooling initiation. Billing concludes upon completion of data burning, cleaning of experimental supplies, and software logout, with immediate return of the access card required.</li>
<li class="ed_txt">Due to the high cost of CCDs and the risk of moisture condensation from frequent temperature cycling, consecutive reservations for the same experiment on the same day shall be charged from the initial software launch. The software must remain open throughout to prevent CCD heating and moisture condensation. Billing concludes upon completion of the final session on that day. ** Example: Tracking tracer metabolism in a living organism at hourly intervals over four hours. The fee period begins when the software is logged in, and CCD cooling starts. The fee settlement time is after the final session is completed, including burning the results, cleaning experimental equipment, and logging out of the software.</li>
<li class="ed_txt">Off-campus users must first undergo a commissioned service for their initial use of this machine. Technical personnel will operate the equipment and conduct technical proficiency assessments for off-campus users who have received prior training, enabling them to operate independently in the future. Therefore, the hourly usage fee for off-campus users during their first session is NT$3,000 + NT$4,500 = NT$7,500. After passing the assessment, future use of this machine will not require any more service. The fee will be charged according to the standard rate: NT$3,000 per hour for non-university personnel.</li>
<li class="ed_txt">Off-campus individuals wishing to operate the equipment independently must first undergo training and pass an assessment. Qualified individuals must present valid identification for verification of eligibility to use the equipment.</li>
<li class="ed_txt">Off-campus entities wishing to use this equipment must have their experimental animals housed at the Experimental Animal Center on the Hsinchu Bo-Ai Campus of this university to schedule usage.</li>
</ol>
</div>Management and Usage<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>Instrument usage regulations:</strong></div>
<ol>
<li class="ed_txt">This instrument is designed for general tissue or cell samples. If you want to experiment with other infectious samples, please talk about it with the technical operator first.</li>
<li class="ed_txt">Wearing gloves while operating computers is strictly prohibited.</li>
<li class="ed_txt">The standard operating procedures must be followed while using the instrument. Please make sure to comply with the instrument usage regulations. Failure to comply with the rules three times will result in suspension of the right to use.</li>
<li class="ed_txt">Please thoroughly clean the instrument and operating surface after use. Fill out the instrument usage registration form and notify the instrument administrator to conduct an inspection (clean with 70% alcohol).</li>
<li class="ed_txt">If the instrument malfunctions, please let the technical personnel know as soon as possible. Please don't try to disassemble or assemble the instrument yourself. Inform the technical operator or instrument manager of the instrument failure immediately. You must bear the repair costs if the instrument is damaged due to personal use.</li>
<li class="ed_txt">You can only use Isoflurane in gas anesthesia devices.</li>
<li class="ed_txt">To access image-related data, bring your own DVD burner. Saving files on the computer and using USBs are strictly prohibited. Violators will have their right to use it suspended for one month.</li>
<li class="ed_txt">If you publish papers in journals using IVIS equipment, you can offset the one-time usage fee.</li>
</ol>
<div class="ed_txt"><strong>Instrument Management </strong></div>
<ol>
<li class="ed_txt">The instrument is managed by full-time faculty members with experience operating it in the College of Engineering Bioscience. Relevant personnel, funding, and usage issues are discussed with full-time faculty members from the College of Engineering Bioscience who have experience operating the instrument.</li>
<li class="ed_txt">Personnel, funding, and charging standards must be submitted to the Department's Resource Committee for resolution and implemented after approval by the Department Affairs Meeting.</li>
<li class="ed_txt">At least one or two seminars are held annually for education and training. If necessary, various training fees may be charged.</li>
<li class="ed_txt">The instrument has an assistant for equipment management and maintaining the surrounding environment. Depending on usage conditions, it will be decided whether to increase the workforce.</li>
<li class="ed_txt">The instrument has several instrument seed instructors. They are postgraduate students with certification and operating licenses (issued by the instrument manufacturer) who can lead and assist users in operating the instrument. In principle, seed instructors can be paid with a work-study allowance. However, no salary will be paid if the seed instructor leads their own laboratory users to operate the instruments.</li>
</ol>
</div>Training Application and Reservation<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>Terms of use:</strong></div>
<ol>
<li class="ed_txt">Users are required to pass a certification to use it</li>
<li class="ed_txt">Participate in the "IVIS Usage Principles" and "IVIS Hands-on Training" courses and pass the assessment to obtain a certification to use it yourself.<br />
Note: This instrument holds at least one or two seminars annually for education and training. If necessary, various training fees may be charged.</li>
</ol>
<div class="ed_txt"><strong>Instrument Reservation:</strong></div>
<ol>
<li class="ed_txt">Users MUST make reservations one week before and submit the application form before use.</li>
<li class="ed_txt">After the reservation is confirmed, you must notify the cancellation three days before use if you cannot use it for any reason. If you do not cancel at least 3 days in advance, you will be considered to have used the reservation period and will still have to pay.</li>
</ol>
<div class="ed_txt"><strong>Note:</strong></div>
<ol>
<li class="ed_txt">Charges will be calculated from the reservation time. Exceeding 10 minutes will be counted as one hour. If the previous user's use delays you, this time will not be included in your reservation time.</li>
<li class="ed_txt">If you are 30 minutes late for your scheduled reservation, your time slot may be given to other users who need to use the machine. If you encounter a problem with the experiment and cannot use the machine, please cancel your reservation as soon as possible. If you do not cancel, you will still be charged the full fee for your reservation period.</li>
<li class="ed_txt">If you need to cancel your reservation, please notify us at least three days in advance. You will not receive a refund if you cancel less than three days in advance. Please do not cancel without a valid reason, as this wastes the workforce, time, medicine, and laser life.</li>
<li class="ed_txt">If you participate in regularly held training courses, you will not be charged a teaching fee. However, you will be charged a teaching fee if you request teaching outside of the teaching hours.</li>
<li class="ed_txt">After completing training and passing the assessment, you can operate and use the instrument independently. Please review the charging standards above.</li>
<li class="ed_txt">Our charging standards are recalculated every January and July. If adjustments are made, we will announce them separately.</li>
</ol>
</div>
<div class="ed_model17 clearfix ed_list">
<ul>
<li class="d-flex"><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">IVIS Reservation and Use Affidavit</span></span>
<ul class="d-flex">
<li><a href="/userfiles/ordch/files/20231013163925232.odt" rel="noreferrer noopener" target="_blank" title="Attachment-IVIS reservation and use cut-off book (odt) (open a new window) "><img alt="Attachment-IVIS reservation and use cut-off book" src="/userfiles/file/odt.png" /> </a></li>
</ul>
</li>
</ul>
</div>https://www.nycu.edu.tw/ord/en/app/machine/image?module=machine&detailNo=1356094876696973312&init=YIVIS Lumina S5 Imaging Systemhttps://ord.edu.tw/ord/en/app/artwebsite/view?module=artwebsite&id=2021&serno=ebdd9934-00ef-4bee-9a8a-11f305100505Instrument List of Guangfu and Boai Campushttps://www.nycu.edu.tw/ord/en/app/machine/list?module=machine&id=2038Biomedical Imaging
- <![CDATA[[Boai] Non-invasive 3D in vivo molecular imaging system]]><![CDATA[<div class="ed_model05 clearfix">
<div class="ed_pic_right"><img alt="Non-invasive 3D in vivo molecular imaging system" src="/userfiles/ordch/images/20231013162806959.jpg" /></div>
<ul>
<li class="ed_txt"><strong>Caliper Spectrum IVIS System, IVIS system</strong>
<ul>
<li class="ed_txt">Model: Caliper Spectrum</li>
</ul>
</li>
<li class="ed_txt"><strong>Spectral Instruments Imaging</strong>
<ul>
<li class="ed_txt">Model: Ami HTX</li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument expert: </strong>
<ul>
<li class="ed_txt"><strong>Prof. Chao, Jui-I</strong>
<ul>
<li class="ed_txt">Extension 56965</li>
</ul>
</li>
<li class="ed_txt"><strong>Prof. Chao, Chi-Hong</strong>
<ul>
<li class="ed_txt">Extension 59725</li>
</ul>
</li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument Operation Technician: Wang, Cing-Hong [full time]</strong>
<ul>
<li class="ed_txt">Extension 56939</li>
<li class="ed_txt">E-mail <a href="mailto:mailto:chwang.bt10@nycu.edu.tw" title="chwang.bt10@nycu.edu.tw">chwang.bt10@nycu.edu.tw</a></li>
</ul>
</li>
<li class="ed_txt"><strong>Contact Person: MS. Chen, I-Jing</strong>
<ul>
<li class="ed_txt">Extension 56941</li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument Location</strong>: Room 743, Hsien Chee Bio-ICT Building</li>
</ul>
<div class="ed_txt"> </div>
</div>]]>Instrumentation Resource Center 2026-01-27Introduction<div class="ed_model01 clearfix">
<div class="ed_txt"><span style="font-size:120%;">1. <strong>Non-invasive 3D in vivo molecular imaging system</strong></span><br />
<strong>Instrument brand, model, year of purchase</strong></div>
<ul>
<li class="ed_txt">Brand: Caliper</li>
<li class="ed_txt">Model: Spectrum</li>
<li class="ed_txt">Purchase date: September 2010</li>
</ul>
<div class="ed_txt"><strong>Important Specifications</strong></div>
<ul>
<li class="ed_txt">IVIS Spectrum System: 3D in vivo molecular imaging system</li>
<li class="ed_txt">XGI-8 Anesthesia System</li>
<li class="ed_txt">Image Analysis Computer </li>
<li class="ed_txt">Resolution 2048×2048</li>
<li class="ed_txt">Detection range 400nm-900m (can be applied to various luminescence/fluorescent imaging)</li>
<li class="ed_txt">Field size 3.9 x 3.9 cm ~ 23 x 23 cm</li>
<li class="ed_txt">Sensitivity: <70 p/s/sr/cm2</li>
<li class="ed_txt">Gas anesthesia system</li>
<li class="ed_txt">Heated lifting photography platform for small animals</li>
<li class="ed_txt">Fluorescent light source</li>
<li class="ed_txt">Luminescnec/fluorescence 3D analysis</li>
<li class="ed_txt">Fluorescence detection filter
<ul>
<li class="ed_txt">Excitation filters: 415-445, 445-480, 480-520, 520-550, 550-580, 580-620, 620-650, 650-680, 680-720, 720-760 (nm)</li>
<li class="ed_txt">Emission filters: 490-510, 510-530, 530-550, 550-570, 570-590, 590-610, 610-630, 630-650, 650-670, 670-690 , 690-710, 710-730, 730-750, 750-770, 770-790, 790-810, 810-830, 830-850(nm)</li>
</ul>
</li>
</ul>
<div class="ed_txt"><span style="font-size:120%;"><strong>2. In vivo luminescent fluorescent system</strong></span><br />
<strong>Instrument brand, model, year of purchase</strong></div>
<ul>
<li class="ed_txt">Brand: Spectral Instruments Imaging</li>
<li class="ed_txt">Model: Ami HTX</li>
<li class="ed_txt">Purchase period: December 2010</li>
</ul>
<div class="ed_txt"><strong>Important Specifications</strong></div>
<ul>
<li class="ed_txt">Ami HTX host</li>
<li class="ed_txt">Animal gas anesthesia system (VetEquip RC2+)</li>
<li class="ed_txt">Image Analysis Computer</li>
<li class="ed_txt">Resolution 1152 x 770</li>
<li class="ed_txt">Field Size: 25 x 17 cm~10 x 7 cm</li>
<li class="ed_txt">Applicable to various luminescent/fluorescent imaging</li>
<li class="ed_txt">Fluorescence detection filter:
<ul>
<li class="ed_txt">Excitation light source: 430, 465, 500, 535, 570, 605, 640, 675, 710, 745 nm;</li>
<li class="ed_txt">Ten emission filters: 530, 610, 650, 670, 690, 710, 750, 790, 830, 850 nm</li>
</ul>
</li>
<li class="ed_txt">X-ray module
<ul>
<li class="ed_txt">X-ray camera: Line scanning imager</li>
<li class="ed_txt">X-ray intensity: 10-40keV</li>
<li class="ed_txt">X-ray photography range: 25 x 15 cm</li>
<li class="ed_txt">Can be automatically integrated with luminescent/fluorescent images</li>
</ul>
</li>
</ul>
</div>Services and Opening Hours<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>Services</strong></div>
<ol>
<li class="ed_txt">Absolute quantitative analysis and measurement of luminescence for non-living vertebrate animals and plants </li>
<li class="ed_txt">Absolute quantitative analysis and measurement of fluorescence for non-living vertebrate animals and plants </li>
<li class="ed_txt">Absolute quantitative analysis and measurement of luminescence cell lines</li>
<li class="ed_txt">Absolute quantitative analysis and measurement of luminescent strains</li>
<li class="ed_txt">Absolute quantitative analysis and measurement of fluorescent cell lines.</li>
<li class="ed_txt">Absolute quantitative analysis and measurement of fluorescent strains.</li>
<li class="ed_txt">Three-dimensional image reconstruction and signal depth detection </li>
<li class="ed_txt">Mouse animal organ model set and signal position analysis </li>
<li class="ed_txt">3D image output </li>
<li class="ed_txt">Multi-fluorescence analysis and automatic background subtraction </li>
</ol>
<div class="ed_txt">
<div class="ed_model19 clearfix"><strong>Opening Hours</strong></div>
<ol>
<li class="ed_model19 clearfix">Monday to Thursday: 9:00 – 17:00</li>
<li class="ed_model19 clearfix">Friday: 9:00 – 1200</li>
</ol>
</div>
</div>System Open Level<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>System Open Level</strong></div>
<ol>
<li class="ed_txt">General working hours: Level B</li>
<li class="ed_txt">Night and holiday periods: Level C</li>
</ol>
<div class="ed_txt"><strong><u>System Level Description</u></strong></div>
<ul>
<li class="ed_txt">Level A: Open to students who need to use it. They can operate it on their own after training and assessment.</li>
<li class="ed_txt">Level B: Each professor nominates one student for training, while the rest operate under those who have been trained. Professors with multiple students using the instrument can request an increase in the number of students receiving training.</li>
<li class="ed_txt">Level C: The instrument administrator selects several students recommended by the professor to receive training. After passing the assessment, they can self-operate the instrument and be responsible for delegated operation service.</li>
<li class="ed_txt">Level D: The laboratory's technical staff only accept delegated services and are unavailable for general use.</li>
</ul>
</div>Charges<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>Charging standards</strong></div>
<ol>
<li class="ed_txt"><strong>Non-invasive 3D in vivo molecular imaging system</strong>
<ul>
<li class="ed_txt">On-campus: NT$750/hour (please prepare your own Isoflurane)</li>
<li class="ed_txt">Off-campus: NT$2,000/hour (please prepare your own Isoflurane)</li>
</ul>
</li>
<li class="ed_txt"><strong>In vivo luminescent fluorescent system</strong>
<ul>
<li class="ed_txt">On-campus: NT$300/hour (please prepare your own Isoflurane)</li>
<li class="ed_txt">Off-campus: NT$1,000/hour (please prepare your own Isoflurane)</li>
</ul>
</li>
</ol>
</div>Management and Usage<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>Instrument usage regulations:</strong></div>
<ol>
<li class="ed_txt">This instrument is designed for general tissue or cell samples. If you intend to experiment with other infectious samples, please discuss it with the technical operator first.</li>
<li class="ed_txt">Wearing gloves while operating computers is strictly prohibited.</li>
<li class="ed_txt">The standard operating procedures must be followed while using the instrument. Please make sure to comply with the instrument usage regulations. Failure to follow the regulations three times will suspend the right to use.</li>
<li class="ed_txt">Please thoroughly clean the instrument and operating surface after use. Fill out the instrument usage registration form and notify the instrument administrator to conduct an inspection (clean with 70% alcohol).</li>
<li class="ed_txt">If the instrument malfunctions, please inform the technical personnel immediately. Do not attempt to disassemble or assemble the instrument yourself. Inform the technical operator or instrument manager of the instrument failure immediately. You must bear the related repair costs if the instrument is damaged for personal reasons.</li>
<li class="ed_txt">You can only use Isoflurane in gas anesthesia devices.</li>
<li class="ed_txt">To access image-related data, bring your own DVD burner. Saving files on the computer and USB access are strictly prohibited. Violators will have their right to use it suspended for one month.</li>
<li class="ed_txt">If you publish papers in journals using IVIS equipment, you can offset the one-time usage fee.</li>
</ol>
<div class="ed_txt"><strong>Instrument Management </strong></div>
<ol>
<li class="ed_txt">The instrument is managed by full-time faculty members with experience operating it in the College of Life Science. Relevant personnel, funding, and usage issues are discussed with full-time faculty members with experience operating the instrument from the College of Life Science.</li>
<li class="ed_txt">Personnel, funding, and charging standards must be submitted to the Department's Resource Committee for resolution and implemented after approval by the Department Affairs Meeting.</li>
<li class="ed_txt">At least one or two seminars are held annually for education and training. If necessary, various training fees may be charged.</li>
<li class="ed_txt">The instrument has an assistant for equipment management and maintaining the surrounding environment. Depending on usage conditions, it will be decided whether to increase manpower.</li>
<li class="ed_txt">The instrument has several instrument seed instructors. They are postgraduate students with certification and operating licenses (certified and issued by the instrument manufacturer) who can lead and assist users in operating the instrument. In principle, seed instructors can be paid with a work-study allowance. However, no salary will be paid if the seed instructor leads their own laboratory users to operate the instruments.</li>
</ol>
</div>Training Application and Reservation<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>Term of use:</strong></div>
<ol>
<li class="ed_txt">Users are required to pass certification to use it</li>
<li class="ed_txt">Participate in the "IVIS Usage Principles" and "IVIS Hands-on Training" courses and pass the assessment to obtain a certification to use it yourself.<br />
Note: This instrument holds at least one or two seminars annually for education and training. If necessary, various training fees may be charged.</li>
</ol>
<div class="ed_txt"><strong>Instrument Reservation:</strong></div>
<ol>
<li class="ed_txt">Users MUST make reservations one week before and submit the application form before use.</li>
<li class="ed_txt">After the reservation is confirmed, you must notify the cancellation three days before use if you cannot use it for any reason. If you do not cancel three days in advance, you will be regarded as using the reservation period and still have to pay.</li>
</ol>
<div class="ed_txt"><strong>Note:</strong></div>
<ol>
<li class="ed_txt">Charges will be calculated from the reservation time. Exceeding 10 minutes will be counted as one hour. If you are delayed due to the previous user's use, this will not be included in your reservation time.</li>
<li class="ed_txt">If you are 30 minutes late for your scheduled reservation, your time slot may be given to other users who need to use the machine. If you encounter a problem with the experiment and cannot use the machine, please cancel your reservation immediately. If you do not cancel, you will still be charged the full fee for your reservation period.</li>
<li class="ed_txt">If you need to cancel your reservation, please notify us at least three days in advance. You will not receive a refund if you cancel less than three days in advance. Please do not cancel without a valid reason, as this wastes manpower, time, medicine, and laser life.</li>
<li class="ed_txt">If you participate in regularly held training courses, you will not be charged a teaching fee. However, you will be charged a teaching fee if you request teaching outside of the teaching hours.</li>
<li class="ed_txt">After completing training and passing the assessment, you can operate and use the instrument independently. Please refer to the above charging standards.</li>
<li class="ed_txt">Our charging standards are recalculated every January and July. If adjustments are made, we will announce them separately.</li>
</ol>
</div>
<div class="ed_model17 clearfix ed_list">
<ul>
<li class="d-flex"><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">IVIS Reservation and Use Affidavit</span></span>
<ul class="d-flex">
<li><a href="/userfiles/ordch/files/20231013163925232.odt" rel="noreferrer noopener" target="_blank" title="Attachment-IVIS reservation and use cut-off book (odt) (open a new window) "><img alt="Attachment-IVIS reservation and use cut-off book" src="/userfiles/file/odt.png" /> </a></li>
</ul>
</li>
</ul>
</div>https://www.nycu.edu.tw/ord/en/app/machine/image?module=machine&detailNo=1168787194802868224&init=YNon-invasive 3D in vivo molecular imaging systemhttps://ord.edu.tw/ord/en/app/artwebsite/view?module=artwebsite&id=2021&serno=ebdd9934-00ef-4bee-9a8a-11f305100505Instrument List of Guangfu and Boai Campushttps://www.nycu.edu.tw/ord/en/app/machine/list?module=machine&id=2038Biomedical Imaging
- <![CDATA[[Guangfu] Brain Function Imaging System (BFIS)]]><![CDATA[<div class="ed_model05 clearfix">
<div class="ed_pic_right"><img alt="Brain function neuroimaging system" src="/userfiles/ordch/images/20231016091929375.jpg" /></div>
<ul>
<li class="ed_txt"><strong>Brain Function Imaging System, BFIS</strong>
<ul>
<li class="ed_txt">Functional near-infrared spectrometer
<ul>
<li class="ed_txt">Brand & Model: NirX, NirScout</li>
</ul>
</li>
<li class="ed_txt">EEG magnifier
<ul>
<li class="ed_txt">Brand & Model: Compumedics, Neuroscan NuAmp</li>
</ul>
</li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument Expert: Prof. Ko, Li-Wei</strong>
<ul>
<li class="ed_txt">Ext. 54341</li>
<li class="ed_txt">Email <a href="mailto:lwko@nycu.edu.tw" title="lwko@nycu.edu.tw">lwko@nycu.edu.tw</a></li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument Operation Technician: Wu, Yu-Chi</strong>
<ul>
<li class="ed_txt">Ext. 54413</li>
<li class="ed_txt">Email <a href="mailto:tigerwu1227ssl@gmail.com" title="tigerwu1227ssl@gmail.com">tigerwu1227ssl@gmail.com</a></li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument Reservation: <a href="mailto:mailto:tigerwu1227ssl@gmail.com" title="Yu-Chi Wu">Yu-Chi Wu</a>, <a href="mailto:mailto:Jaillofish128.bt08@nycu.edu.tw" title="Cheng-Hua Su">Cheng-Hua Su</a></strong>
<ul>
<li class="ed_txt">Ext. 54413</li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument Location: Room 808, Engineering Building V</strong></li>
</ul>
</div>]]>Instrumentation Resource Center 2025-02-20Introduction<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>This instrument consists of a functional near-infrared spectrometer and an electroencephalogram magnifier.<br />
<br />
Instrument brand, model, year of purchase</strong></div>
<ul>
<li class="ed_txt">Functional near-infrared spectrometer
<ul>
<li class="ed_txt">Brand: NirX</li>
<li class="ed_txt">Model: NirScout</li>
<li class="ed_txt">Purchase period: 2012/11/06</li>
</ul>
</li>
<li class="ed_txt">EEG magnifier
<ul>
<li class="ed_txt">Label: Compumedics</li>
<li class="ed_txt">Model: Neuroscan NuAmp</li>
<li class="ed_txt">Purchase period: 2004/05/18</li>
</ul>
</li>
</ul>
<div class="ed_txt"><strong>Important Specifications</strong></div>
<ul>
<li class="ed_txt">Functional near-infrared spectrometer
<ul>
<li class="ed_txt">Source NSC 8*16 / 8*8 LED sources</li>
<li class="ed_txt">Source Wavelengths 760nm & 850nm</li>
<li class="ed_txt">Detection Sensor Silicon Photodiode (SiPD)</li>
<li class="ed_txt">Detector Sensitivity < 1 pW</li>
<li class="ed_txt">Sampling Rate 2.5 – 100 Hz</li>
<li class="ed_txt">Temperature Range 10 – 40 C (operating)</li>
</ul>
</li>
<li class="ed_txt">EEG magnifier
<ul>
<li class="ed_txt">Analog inputs 40 unipolar (bipolar derivations can be computed)</li>
<li class="ed_txt">Sampling frequencies 125, 250, 500, 1000 Hz per channel, software selectable for all channels</li>
<li class="ed_txt">A/D resolution22 bits</li>
<li class="ed_txt">Full-scale input range ±130 mV</li>
<li class="ed_txt">Interface Universal Serial Bus (USB),</li>
</ul>
</li>
</ul>
</div>Services and Opening Hours<div class="ed_model06 clearfix">
<div class="table01">
<table class="ed_table caption-top" summary="service items">
<caption>Services</caption>
<tbody>
<tr>
<th>Item </th>
<th>Service Content </th>
<th>Related Fields</th>
</tr>
<tr>
<td class="ed_pc_center" data-th="service items">Near-infrared brain activity measurement </td>
<td data-th="Service Content">To measure and analyze subjects' brain activity in static experiments with near-infrared devices </td>
<td data-th="Use a school">Neuroscience, Cognitive Science, Psychology</td>
</tr>
<tr>
<td class="ed_pc_center" data-th="service items">EEG brain activity measurement </td>
<td data-th="Service Content">To measure and analyze subjects' brain activity in a static experiment with an EEG imaging device</td>
<td data-th="Use a school">Neuroscience, Cognitive Science</td>
</tr>
</tbody>
</table>
<br />
<strong>Opening hours: </strong>Monday to Friday, 9:30-18:00</div>
</div>System Open Level<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>System open level</strong></div>
<ol>
<li class="ed_txt">General working hours: Level A</li>
<li class="ed_txt">Night and holiday period: not open</li>
</ol>
<div class="ed_txt"><br />
<u><strong>System Level Description</strong></u></div>
<ul>
<li class="ed_txt">Level A: Open to students who need to use it. They can operate it on their own after training and assessment.</li>
<li class="ed_txt">Level B: Each professor nominates one student for training, while the rest operate under those who have been trained. Professors with multiple students using the instrument can request an increase in the number of students receiving training.</li>
<li class="ed_txt">Level C: The instrument administrator selects several students recommended by the professor to receive training. After passing the assessment, they can self-operate the instrument and be responsible for delegated operation service.</li>
<li class="ed_txt">Level D: The laboratory's technical staff only accept delegated services and are unavailable for general use.</li>
</ul>
</div>Charges<div class="ed_model06 clearfix">
<div class="table01">
<table class="ed_table caption-top" summary="Charges">
<caption>Charges</caption>
<tbody>
<tr>
<th>Self-operation </th>
<th>Academic Units<br />
(Universities and Colleges) </th>
<th>Industry and other research units</th>
</tr>
<tr>
<td class="ed_pc_center" data-th="Self-operated charges">Near-infrared brain activity measurement</td>
<td data-th="Academic Units (Universities and Colleges) ">NT$500/hour</td>
<td data-th="Manufacturers and research units">NT$500/hour</td>
</tr>
<tr>
<td class="ed_pc_center" data-th="Self-operated charges">Observation of brain activity of limb movement</td>
<td data-th="Academic Units (Universities and Colleges) ">NT$500/hour</td>
<td data-th="Manufacturers and research units">NT$500/hour</td>
</tr>
</tbody>
</table>
</div>
</div>Management and Usage<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>Instrument Usage Regulations:</strong></div>
<ol>
<li class="ed_txt">this equipment can only be used after reservation and confirmation with the instrument operating technician one week in advance.</li>
<li class="ed_txt">Each time the system is used, it should be confirmed whether the instrument system is normal. After use, users must sign on to the use record log. If there are any issues, the instrument administrator should be notified immediately to avoid disputes over usage and clarify responsibility.</li>
<li class="ed_txt">Users are responsible for restoring the instrument and turning off the power after use, and can leave only after confirmation by the management staff.</li>
<li class="ed_txt">For those who violate the above norms and still cooperate after verbal warnings, the administrator may suspend the use of the employee according to the circumstances.</li>
</ol>
<div class="ed_txt"><span style="font-size:120%;"><strong>Instrument operation Reservation</strong></span></div>
</div>
<hr class="ed_border01" />
<div class="ed_model22 clearfix">
<div class="ed_model22 clearfix">
<div class="row w-100 mx-0">
<ul class="col-12 col-md-6">
<li class="full-name">Wu, Yu-Chi</li>
<li class="li"><img alt="phone" src="/userfiles/editor/ic_phone.svg" />＃54413</li>
<li class="li"><img alt="mail" src="/userfiles/editor/ic_mail.svg" /> <a href="mailto:tigerwu1227ssl@gmail.com" title="tigerwu1227ssl@gmail.com">tigerwu1227ssl@gmail.com</a></li>
</ul>
</div>
</div>
</div>
<div class="ed_model22 clearfix">
<div class="ed_model22 clearfix">
<div class="row w-100 mx-0">
<ul class="col-12 col-md-6">
<li class="full-name">Su, Cheng-Hua</li>
<li class="li"><img alt="phone" src="/userfiles/editor/ic_phone.svg" />＃54413</li>
<li class="li"><img alt="mail" src="/userfiles/editor/ic_mail.svg" /> <a href="mailto:Jaillofish128.bt08@nycu.edu.tw" title="Jaillofish128.bt08@nycu.edu.tw">Jaillofish128.bt08@nycu.edu.tw</a></li>
</ul>
</div>
</div>
</div>https://www.nycu.edu.tw/ord/en/app/machine/image?module=machine&detailNo=1168431906832781312&init=YBrain Function Imaging Systemhttps://ord.edu.tw/ord/en/app/artwebsite/view?module=artwebsite&id=2021&serno=ebdd9934-00ef-4bee-9a8a-11f305100505Instrument List of Guangfu and Boai Campushttps://www.nycu.edu.tw/ord/en/app/machine/list?module=machine&id=2038Biomedical Imaging
- <![CDATA[[YangMing] Small animal optical imaging system: Biospace Lab PhotonIMAGER Optima]]><![CDATA[<div class="ed_model05 clearfix">
<div class="ed_pic_right"><img alt="Small Animal Optical Imaging System" src="/userfiles/ordch/images/20231013170237405.png" /></div>
<ul>
<li class="ed_txt"><strong>Biospace Lab PhotonIMAGER Optima</strong></li>
<li class="ed_txt"><strong>Instrument Location: East side of Experimental Animal Center, Yangming Campus</strong></li>
<li class="ed_txt"><strong>Administrator: Prof. Lin, Ching-po </strong>
<ul>
<li class="ed_txt">Campus extension 67338</li>
</ul>
</li>
<li class="ed_txt"><strong>Management unit: Yang-Ming Campus </strong><a href="https://saic.brc.nycu.edu.tw/optima-2/" rel=" noreferrer noopener" target="_blank" title="Small Animal Imaging Core Facility of Brain Science Research Center(Open a new window)">Small Animal Imaging Core Facility of Brain Science Research Center</a>
<ul>
<li class="ed_txt">Office Location: Room 532, 5th Floor, Traditional Medicine Building A</li>
<li class="ed_txt">E-mail: <a href="mailto:nycu.saic@gmail.com" title="nycu.saic@gmail.com">nycu.saic@gmail.com</a><!-- li--></li>
<li class="ed_txt">Extension 65293</li>
</ul>
</li>
</ul>
<div class="ed_txt"> </div>
</div>]]>Instrumentation Resource Center 2025-01-15Instrument Introduction<div class="ed_model01 clearfix">
<div class="ed_txt">Optima has high-sensitivity imaging technology, which can go from general two-dimensional to three-dimensional imaging, and even has exclusive real-time dynamic imaging (real-time) and awake mode. Depending on the experimental design, researchers can use luminescence or fluorescent labeling technology to study research objects, such as genes, tumor cells, stem cells, antibodies, drugs, etc. It can be used in cancer research, new drug development, nanomaterial research, establishment of disease animal models, neurological function research, stem cell research, etc.</div>
</div>Application Examples<div class="ed_model04 clearfix">
<div class="ed_flex_box">
<div class="box">
<div class="ed_pic"><img alt="Cold light imaging (BLI)" src="/userfiles/ordch/images/20231013170500248.jpg" /></div>
<div class="ed_title02">Luminescence imaging (BLI)</div>
</div>
<div class="box">
<div class="ed_pic"><img alt="Fluorescence contrast (GFP)" src="/userfiles/ordch/images/20231013170520591.jpg" /></div>
<div class="ed_title02">Fluorescence imaging (GFP)</div>
</div>
<div class="box">
<div class="ed_pic"><img alt="Multi-probe imaging (BLI+GFP)" src="/userfiles/ordch/images/20231013170538708.jpg" /></div>
<div class="ed_title02">Multi-probe imaging (BLI+GFP)</div>
</div>
</div>
</div>
<hr class="ed_border01" />
<div class="ed_model12 clearfix">
<div class="ed_title01">Absolute quantitative analysis and measurement of luminescence and fluorescence</div>
<div class="ed_flex_box">
<div class="ed_pic"><img alt="Luminescence and fluorescence absolute quantitative analysis and measurement function" src="/userfiles/ordch/images/20231013170806510.jpg" />
<div class="ed_txt">Absolute quantitative analysis and measurement functions of luminescence and fluorescence</div>
</div>
<div class="ed_pic"><img alt="Luminescence, fluorescence absolute quantitative analysis, measurement function-profile" src="/userfiles/ordch/images/20231013170847947.png" />
<div class="ed_txt">Intensity profile</div>
</div>
</div>
<div class="ed_flex_box">
<div class="ed_pic"> </div>
</div>
</div>
<hr class="ed_border01" />
<div class="ed_model12 clearfix">
<div class="ed_title01">With real-time dynamic imaging, pharmacokinetic analysis can be performed.</div>
<div class="ed_flex_box">
<div class="ed_pic"><img alt="With real-time dynamic imaging, pharmacokinetic analysis can be performed" src="/userfiles/ordch/images/20231013171329315.png" /></div>
<div class="ed_pic"> </div>
</div>
</div>
<hr class="ed_border01" />
<div class="ed_model12 clearfix">
<div class="ed_title01">Simulating three-dimensional in vivo optical and computed tomography fusion images</div>
<div class="ed_flex_box">
<div class="ed_pic"><img alt="Simulating three-dimensional in vivo optical and computed tomography fusion images" src="/userfiles/ordch/images/20231013171222674.png" /></div>
<div class="ed_pic"> </div>
</div>
</div>
<hr class="ed_border01" />
<div class="ed_model12 clearfix">
<div class="ed_title01">Awake mode imaging</div>
<div class="ed_flex_box">
<div class="ed_pic"><img alt="Awake mode imaging" src="/userfiles/ordch/images/20231013171405502.gif" /></div>
<div class="ed_pic"> </div>
</div>
</div>Opening Hours<div class="ed_model01 clearfix">
<ol>
<li class="ed_txt">The current opening hours are from 9 am to 5 pm, Monday to Friday (closed on holidays).</li>
<li class="ed_txt">Other sessions might be open and subject to further announcement based on equipment usage and the status of the technical staff.</li>
</ol>
</div>Reservation and Usage Rules<div class="ed_model01 clearfix">
<div class="ed_txt"><span style="font-size:105%;"><strong>Reservations</strong></span></div>
<ol>
<li class="ed_txt">NYCU and Taipei Veterans General Hospital users can make reservations four weeks before.</li>
<li class="ed_txt">Users from off-campus units can make reservations three weeks in advance.</li>
<li class="ed_txt">All billing and payment procedures must be completed before the experiment. Otherwise, all appointments for the month will be canceled.</li>
<li class="ed_txt">Reservations must be made at least seven days in advance, and the reservation time is in 1-hour increments.</li>
<li class="ed_txt">If you want to cancel the experiment, please log in to the reservation system seven days before the experiment to cancel it yourself; if you cancel 3-6 days before the experiment, half of the reservation time will be deducted; if you cancel within two days before the imaging day, the fee will be charged as usual.</li>
<li class="ed_txt">For new experiments and special requirements, please inform the operator of the experiment content one week before use.</li>
<li class="ed_txt">When the experiment exceeds the reservation time, if there are subsequent reservations, the use can be extended with the consent of the following unit for up to ten minutes. If other units have no subsequent reservation, the user can extend the session. If the extension exceeds twenty minutes, the session will be charged. Use less than one hour is counted as one hour.</li>
<li class="ed_txt">Please arrive on time according to the reserved time slot. Latecomers are not allowed to ask for a delay. Being late for 30 minutes will be considered a no-show, and the reservation will be canceled. The facility will suspend the users who are late or fail to show up repeatedly.</li>
</ol>
<div class="ed_txt"><span style="font-size:105%;"><strong>Specifications for Using the Instrument</strong></span></div>
<ol>
<li class="ed_txt">Due to limited computer storage space, Image files will be retained for up to 30 days.</li>
<li class="ed_txt">Currently, it is open for tissue and cell samples from general animals (bred on behalf of animal centers or in a temporary room approved by the animal center.) We do not provide services for infectious animals and samples.</li>
<li class="ed_txt">The facility only provides imaging services. We do not provide analysis services, contrast agents (CT contrast agent, luminescence, etc....), anesthetics (isoflurane only provides gas anesthesia machines), and consumables (needles, black cardboard, etc....).</li>
<li class="ed_txt">Gas anesthetics other than Isoflurane in gas anesthesia devices are prohibited.</li>
<li class="ed_txt">Users are responsible for any consequences of using Isoflurane anesthesia or administering contrast agents during animal imaging.</li>
<li class="ed_txt">The core facility is not responsible for keeping items deposited by users.</li>
</ol>
</div>Reward Plans<div class="ed_model01 clearfix">
<ol>
<li class="ed_txt">Each full-time NYCU faculty member has two hours of free operation to facilitate the acquisition of preliminary research materials (including the teacher himself, who can only use the free operation quota of three teachers at most).</li>
<li class="ed_txt">Articles published in the name of NYCU and mentioned, thanks to the small animal imaging core facility of NYCU Brain Research Center, can get rewards. Each article will be deducted the usage fee equivalent to impact factor times hours (in rounds, less than one point is calculated by one point). Only one application can be made per article.</li>
<li class="ed_txt">Acknowledgments:<br />
We thank the Molecular Imaging Facility Small Animal Instrument Name and Brain Research Center at National Yang Ming Chiao Tung University for the technical support.</li>
</ol>
</div>Charges and Application Process<div class="ed_model02 clearfix">
<div class="ed_title01">Charging standards</div>
<ul>
<li class="ed_txt">NYCU and Taipei Veterans General Hospital: NT$2,000/hour</li>
<li class="ed_txt">Other academic units: NT$3,000/hour</li>
<li class="ed_txt">Industry: NT$3,000/hour</li>
</ul>
<div class="ed_txt"> </div>
<ul>
<li class="ed_txt">The usage fee does not include the cost of luminescence, contrast agent, gas anesthesia agent, and positron contrast agent.</li>
<li class="ed_txt">The user must prepare related consumables such as luminescence, contrast agent, and isoflurane. The <a href="https://irc.ord.nycu.edu.tw/common_instrument/biomedical-imaging/ photonimager-optima/#contact" rel="noreferrer noopener" target="_blank" title="Small Animal Imaging Core Facility(open in new window)">Small Animal Imaging Core Facility</a> will not provide these.</li>
</ul>
<hr class="ed_border01" />
<div class="ed_title01">Application process</div>
<div class="ed_txt"><a href="https://saic.brc.nycu.edu.tw/opticalcharge/" rel="noreferrer noopener" target="_blank" title="See Small Animal Image Core for details Facility webpage (open a new window)">For details, please see the Small Animal Imaging Core Facility webpage</a></div>
</div>Payment Method<div class="ed_model01 clearfix">
<div class="ed_txt"><strong><span style="font-size:120%;">Payment method (please follow the purchase method and order)</span></strong><br />
<strong>By Cash</strong></div>
<ol>
<li class="ed_txt">Fill out the User Consent Certificate in duplicate and ask the project host to sign or seal it.</li>
<li class="ed_txt">Bring the user consent certificate (in duplicate) to the cashier group to pay (stamp, take receipt).</li>
<li class="ed_txt">Bring the User Consent Certificate (in duplicate), payment receipt, and IACUC certificate to the Small Animal Imaging Core Facility to log in for hours.</li>
</ol>
<div class="ed_txt"><strong>By Check</strong></div>
<ol>
<li class="ed_txt">Fill out the User Consent Certificate in duplicate and ask the project host to sign or seal it.</li>
<li class="ed_txt">Bring the cheque and the user consent certificate (in duplicate) to the cashier team to pay (stamp, take the receipt).</li>
<li class="ed_txt">Bring the User Consent Certificate (in duplicate), payment receipt, and IACUC certificate to the Small Animal Imaging Core Facility to log in for hours.</li>
</ol>
<div class="ed_txt"><strong>On-Campus Loan Methods</strong></div>
<ol>
<li class="ed_txt">Fill in the user certificate in duplicate, ask the project host to sign or seal it, and fill in the school loan slip in the accounting requisition system.<br />
(Pre-loan application and write-off → payee details → beneficiary code key in "000" → NYCU internal transfer).</li>
<li class="ed_txt">Prepare documents of on-campus loan slip and user consent certificate to the Small animal imaging core facility Office - Stamped (the stamped certificate is the loan voucher).</li>
<li class="ed_txt">After completing item (2), hold the on-campus loan receipt and loan voucher (with small animal imaging core facility certificate after the office seal) to the Accounting Office to apply for the loan.</li>
<li class="ed_txt">After completing item (3), wait approximately three to four weeks for the cashier team to notify you to collect your receipt.<br />
Please prepare the following documents: the original copy of the user certificate (in duplicate) and the cashier's seal.</li>
<li class="ed_txt">Present receipt, User Consent Certificate (in duplicate) stamped by the Cashier team, and IACUC attestation to the Small animal imaging core facility to log in for hours.</li>
</ol>
</div>
<hr />
<div class="ed_model17 clearfix ed_list">
<ul>
<li class="d-flex"><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">Reference document for sending a letter of inter-school remittance</span> </span>
<ul class="d-flex">
<li><a href="/userfiles/orden/files/20231226161441647.odt" rel="noreferrer noopener" target="_blank" title="Open New Windows"><img alt="Reference document for sending letter of inter-school remittance" src="/userfiles/file/odt.png" /> </a></li>
</ul>
</li>
</ul>
</div>https://www.nycu.edu.tw/ord/en/app/machine/image?module=machine&detailNo=1168783715258601472&init=Y小動物光學影像系統 Biospace Lab PhotonIMAGER Optimahttps://ord.edu.tw/ord/en/app/artwebsite/view?module=artwebsite&id=2023&serno=da69be39-dc4e-48d6-9168-7c96b2dbdb6eInstrument List of YM Campushttps://www.nycu.edu.tw/ord/en/app/machine/list?module=machine&id=2038Biomedical Imaging
- <![CDATA[[YangMing] Small animal positron and MRI instrument: Bruker 7T PET/MR]]><![CDATA[<div class="ed_model05 clearfix">
<div class="ed_pic_right"><img alt="Small animal positron and nuclear magnetic resonance imaging equipment" src="/userfiles/ordch/images/20231016091216587.png" /></div>
<div class="ed_model01 clearfix">
<ul>
<li class="ed_txt"><strong>Model: Bruker 7T PET/MR</strong></li>
<li class="ed_txt"><strong>Instrument Location: 2nd Floor, Old Positron Center (Cyclotron Center), Taipei Veterans General Hospital</strong>
<ul>
<li class="ed_txt">The independent entrance of the building is located on the hillside behind the hospital, adjacent to the Rongyang Tunnel.</li>
<li class="ed_txt">On foot, you can enter from the first floor of the Siyuan Building, take the elevator to the fifth floor of the Siyuan Building, walk towards Zhengzi Center or Spirit Building, and you will see the entrance of Positron Center.</li>
<li class="ed_txt">During the pandemic, the first floor of the Siyuan Building will not be open to traffic. Please enter from the Zhongzheng Building and connect the passage from the second floor of the Zhongzheng Building to the Siyuan Building.</li>
</ul>
</li>
<li class="ed_txt"><strong>Administrator: Prof. Lin Ching-po</strong>
<ul>
<li class="ed_txt">Extension 67338</li>
</ul>
</li>
<li class="ed_txt"><strong>Management unit: Yangming Campus <a href="https://saic.brc.nycu.edu.tw/optima-2/" rel="noreferrer noopener" target="_blank" title="Small Animal Imaging Core of Brain Research Center(Open New Windows)">Small Animal Imaging Core of Brain Research Center</a></strong>
<ul>
<li class="ed_txt">Office Location: Room 532, 5th Floor, Traditional Medicine Building A</li>
<li class="ed_txt">Email: <a href="mailto:nycu.saic@gmail.com" title="nycu.saic@gmail.com">nycu.saic@gmail.com</a></li>
<li class="ed_txt">On-campus extension 65293</li>
<li class="ed_txt">Line account: @268uqyax <a href="https://lin.ee/7X46UWV" rel="noreferrer noopener" target="_blank" title="(Add as friend)(Open New Windows)">(Add as a friend)</a></li>
</ul>
</li>
</ul>
</div>
</div>]]>Instrumentation Resource Center 2025-01-15Introduction<div class="ed_model01 clearfix">
<div class="ed_txt">This instrument is a 7T MRI, which can provide images with higher resolution and higher signal-to-noise ratio (SNR) than traditional 3T MRI.<br />
<br />
<span style="font-size:105%;"><strong>Various functional imaging is possible.</strong></span><br />
<br />
In addition to generating anatomical images of brain soft tissue superior to computed tomography (CT), it can perform various functional imaging, such as brain nerve fiber orientation imaging (DTI), brain angiography, functional imaging, water molecule diffusion Imaging, and animal pathological studies. Combined with ECG and a respiration monitoring system, the artifacts caused by respiration and heartbeat shaking during imaging are minimized, and they can also be synchronized with the heartbeat cycle (Gating) to obtain dynamic cardiac images.<br />
<br />
<span style="font-size:105%;"><strong>With PET's ability to track drug concentrations through radiation, high-resolution functional images can be obtained.</strong></span><br />
<br />
PET obtains high-resolution functional images by tracking the specific accumulation of drugs by radiation. Various functional imaging can be performed depending on the use of monitoring drugs. Such as tracking tumor location and evaluation of malignancy, tracking of the inflammatory response, and research on myocardial perfusion status and neurodegenerative diseases; dynamic imaging can be used to obtain pharmacokinetic studies of drug distribution and metabolism.<br />
<br />
The imaging range of this PET is up to 15 cm, allowing normal-sized mouse images to be imaged in a single session.<br />
<br />
<strong>PET and MR imaging maintain the exact position of the animal and accurately blend the two images to combine molecular-level pathology or functional structures with anatomical images. It is a new tool for non-invasive therapeutic preclinical studies, drug screening, and material research, which can assist in cross-disciplinary imaging studies of small animals.</strong></div>
</div>Application Examples<div class="ed_model01 clearfix">
<div class="ed_txt"><span style="font-size:105%;"><strong>Functional Brain Imaging</strong></span><br />
<br />
By using Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET), it is possible to minimize the differences in individual posture movement during angiography and obtain functional images such as cerebral blood flow and brain inflammation. These functional images can then be superimposed with anatomical images T1 and T2 to obtain brain inflammation (FEPPA), glucose uptake (FDG), and quantitative analysis of tissue blood flow.</div>
</div>
<div class="ed_model04 clearfix">
<div class="ed_flex_box">
<div class="box">
<div class="ed_pic"><img alt="MRI T2 image" src="/userfiles/ordch/images/20231016083128332.jpg" /></div>
<div class="ed_title02">MRI T2 image</div>
</div>
<div class="box">
<div class="ed_pic"><img alt="Cerebral hemorrhage (ASL)" src="/userfiles/ordch/images/20231016083153599.jpg" /></div>
<div class="ed_title02">Cerebral Blood Flow (ASL)</div>
</div>
<div class="box">
<div class="ed_pic"><img alt="PET FEPPA drug imaging" src="/userfiles/ordch/images/20231016083237027.jpg" /></div>
<div class="ed_title02"> PET FEPPA drug imaging</div>
</div>
</div>
</div>
<div class="ed_model01 clearfix">
<div class="ed_txt"><br />
<span style="font-size:105%;"><strong>PET/MR Static and Dynamic Whole Body Imaging</strong></span><br />
<br />
The study utilized MRI and PET scans to minimize the effects of individual posture movement during imaging. A full-body image of a mouse can be obtained in a single imaging session by focusing on the local PET Z-axis and capturing images within a 15 cm range. This method facilitated precise tumor and inflammatory response analysis in animal models by combining functional and anatomical images.<img alt="PET/MR Static and Dynamic Whole-Body Imaging" src="/userfiles/ordch/images/20231016083522817.png" /></div>
<ul>
<li class="ed_txt">On the left is an image of a mouse suffering from rheumatoid arthritis. The inflammation at the joint location of the lesion causes a high glucose uptake, resulting in a high FDG uptake. Analyzing and quantifying the disease model can be done by aligning it with the anatomical MRI T1 image.</li>
<li class="ed_txt">On the right is an image of FEPPA, which binds to the inflammatory receptors of TSPO. This is used to evaluate inflammation models.</li>
</ul>
<div class="ed_txt"><br />
<span style="font-size:105%;"><strong>High-resolution Brain MRI</strong></span><br />
<br />
High-resolution T2 images are used to understand brain structure and analyze brain lesions to facilitate tracking of living animals.<img alt="High-Resolution Brain Magnetic Resonance Imaging" src="/userfiles/ordch/images/20231016083801840.png" /><br />
<br />
<span style="font-size:105%;"><strong>Tumor Tracking</strong></span><br />
<br />
When it comes to tumor tracking, regular T1 and T2 images are used to track the actual status of tumor growth and obtain the tumor type in vivo, the effect on surrounding tissues, and the treatment effect. This helps to achieve the application of long-term tracking in vivo.<br />
<img alt="Tracking Tumor Growth with Periodic T1 and T2 Imaging" src="/userfiles/ordch/images/20231016083913703.png" /><br />
<br />
<span style="font-size:105%;"><strong>PET/MR Dynamic Cardiac Angiography</strong></span><br />
<br />
PET/MR dynamic cardiac angiography uses a system synchronized with the heartbeat and respiratory movements to acquire MRI and PET images of the heart in different cycles. This system enables us to observe the beating of the ventricle and atrium. Additionally, it can be used to determine the anatomy and function of the cardiac muscle cells based on their glucose state. To integrate the acquired images, the black and white MRI background is combined with a colored PET image, resulting in more accurate interpretation and research.<br />
<img alt="MRI Image" src="/userfiles/ordch/images/20231016084147779.png" /><br />
<img alt="PET Image" src="/userfiles/ordch/images/20231016084217775.png" /></div>
</div>Opening Hours<div class="ed_model01 clearfix">
<ol>
<li class="ed_txt">It is open from 9 am to 5 pm, Monday to Friday (closed on holidays).</li>
<li class="ed_txt">The rest of the period will be open after further announcement, depending on the equipment use and the technicians' status.</li>
</ol>
</div>Reservation and Usage Rules<div class="ed_model01 clearfix">
<div class="ed_txt"><span style="font-size:105%;"><strong>Make an appointment</strong></span></div>
<ol>
<li class="ed_txt">NYCU and Taipei Veterans General Hospital users can make reservations four weeks before.</li>
<li class="ed_txt">Users from off-campus units can make reservations three weeks in advance.</li>
<li class="ed_txt">All billing and payment processes must be completed before the experiment. Otherwise, all appointments for the month will be canceled.</li>
<li class="ed_txt">Make reservations at least seven days in advance, and the session is in units of 1 hour.</li>
<li class="ed_txt">If you want to cancel the experiment, please log in to the reservation system seven days before the experiment to cancel it yourself; if you cancel 3-6 days before the experiment, half of the reservation time will be deducted; if you cancel within two days before the imaging day, the fee will be charged as usual.</li>
<li class="ed_txt">For new experiments and special requirements, please inform the operator of the experiment content one week before use.</li>
<li class="ed_txt">When the experiment exceeds the reserved time, if other units are making an appointment later, the use can be extended for up to ten minutes with the consent of the following user. If there is no subsequent appointment by other units, the user can extend the session. If the extension exceeds twenty minutes, the session will be charged. Use less than one hour is counted as one hour.</li>
<li class="ed_txt">Please arrive on time according to the reserved time slot. Latecomers are not allowed to delay operations. If you are 30 minutes late, it will be regarded as a no-show and will not be refunded for the time slot. The facility will suspend the users who are late or fail to show up repeatedly.</li>
</ol>
<div class="ed_txt"><span style="font-size:105%;"><strong>Specifications for Using the Instrument</strong></span></div>
<ol>
<li class="ed_txt">Due to the limited storage space of the computer, the image files can be kept for a maximum of 30 days. The center will not be responsible for file loss due to machine damage.</li>
<li class="ed_txt">Currently, it is open for tissue and cell samples from general animals (bred on behalf of animal centers or in a temporary room approved by the animal center.) Infectious animals and samples are temporarily not allowed to be used.</li>
<li class="ed_txt">We only provide imaging services. Analysis services, contrast agents (CT contrast agent, luminescence, etc....), anesthetics (isoflurane only provides gas anesthesia machines), and consumables (needles, black cardboard, etc....) are not provided.</li>
<li class="ed_txt">Gas anesthesia devices prohibit using gas anesthetics other than Isoflurane.</li>
<li class="ed_txt">Applying for angiography means agreeing to use Isoflurane anesthesia or administering a contrast agent during the animal angiography. The animal may die during the experiment due to physical weakness or other irresistible factors, resulting in abnormal conditions such as hypothermia and respiratory distress.</li>
<li class="ed_txt">The core facility is not responsible for keeping items deposited by users.</li>
</ol>
</div>Reward Plans<div class="ed_model01 clearfix">
<ol>
<li class="ed_txt">Each full-time NYCU faculty member has two hours of free operation to facilitate the acquisition of preliminary research materials (including the teacher himself, who can only use the free operation quota of three teachers at most).</li>
<li class="ed_txt">Articles published in the name of NYCU and mentioned, thanks to the small animal imaging core facility of NYCU Brain Research Center, can get rewards. Each article will be deducted the usage fee equivalent to impact factor times hours (in rounds, less than one point is calculated by one point). Only one application can be made per article.</li>
<li class="ed_txt">Acknowledgments:<br />
We thank the Molecular Imaging Facility Small Animal Instrument Name and Brain Research Center at National Yang Ming Chiao Tung University for the technical support.</li>
</ol>
</div>Charges and Application Process<div class="ed_model01 clearfix">
<div class="ed_txt"><span style="background-color: var(--bs-body-bg); color: var(--bs-body-color); span-family: var(--bs-body-span-family); span-size: var(--bs-body-span-size); span-weight: var(--bs-body-span-weight); text-align: var(--bs-body-text-align);"> </span></div>
</div>
<div class="ed_model06 clearfix">
<div class="table01">
<table class="ed_table caption-top" summary="Charges">
<caption>Charges</caption>
<tbody>
<tr>
<th scope="col">Unit </th>
<th scope="col">NYCU and Taipei Veterans General Hospital </th>
<th scope="col">other academic units </th>
<th scope="col">industry</th>
</tr>
<tr>
<td class="ed_pc_center" data-th="unit of use">usage fee </td>
<td data-th="On-campus and Taipei Veterans General Hospital ">NT$2,500/hour </td>
<td data-th="other academic units ">NT$3,000/hour </td>
<td data-th="industry">NT$5,000/hour</td>
</tr>
</tbody>
</table>
<br />
</div>
</div>
<div class="ed_model01 clearfix">
<ul>
<li class="ed_txt">The equipment usage fee does not include the cost of luminescence, contrast agent, gas anesthesia agent, and positron contrast agent.</li>
<li class="ed_txt">The user must prepare consumables such as luminescent elements, contrast agents, and isoflurane. The small animal imaging core facility will not provide these.</li>
<li class="ed_txt">Positron contrast agent is provided and charged by the Positron Center of Taipei Veterans General Hospital. The small animal imaging core facility will assist with the application. <a href="https://www.nycu.edu.tw/userfiles/ordch/files/20231016085555740.pdf" title="Positrom Contrast Agent Application Process(pdf)">Positron Contrast Agent Application Process</a></li>
</ul>
</div>
<div class="ed_model17 clearfix ed_list">
<ul>
<li class="d-flex"><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">Application process</span></span>
<ul class="d-flex">
<li><a href="https://saic.brc.nycu.edu.tw/petmrcharge/" rel="noreferrer noopener" target="_blank" title="Open New Windows"><img alt="https://saic.brc.nycu.edu.tw/petmrcharge/" src="/userfiles/file/link.png" /> </a></li>
</ul>
</li>
<li class="d-flex"><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">Positron Radiopharmaceutical Application Form</span></span>
<ul class="d-flex">
<li><a href="/userfiles/ordch/files/20231016085446464.odt" rel="noreferrer noopener" target="_blank" title="Open New Windows"><img alt="Positron Radiopharmaceutical Application Form" src="/userfiles/file/odt.png" /> </a></li>
</ul>
</li>
<li class="d-flex"><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">Application And Payment Instructions For Positron Radiopharmaceuticals</span></span>
<ul class="d-flex">
<li><a href="/userfiles/ordch/files/20231016085555740.pdf" rel="noreferrer noopener" target="_blank" title="Open New Windows"><img alt="Application And Payment Instructions For Positron Radiopharmaceuticals" src="/userfiles/file/pdf.png" /></a></li>
</ul>
</li>
</ul>
</div>
<div class="ed_model06 clearfix">
<div class="table01">
<table class="ed_table caption-top" summary="Regular Medication Prices">
<caption>Regular Medication Prices (Unit: NTD)</caption>
<tbody>
<tr>
<th scope="col">Routine medication (times)</th>
<th scope="col">Taipei Veterans General Hospital/Yang Ming</th>
<th scope="col">other academic units</th>
<th scope="col">industry</th>
</tr>
<tr>
<td class="ed_pc_center" data-th="Routine medication (times)">[18F] FDG</td>
<td data-th="President Rong/Yang Ming">3,000</td>
<td data-th="other academic units">3,900</td>
<td data-th="industry">6,000</td>
</tr>
<tr>
<td class="ed_pc_center" data-th="Routine medication (times)">[18F] FBPA<br />
[18F] NaF<br />
[11C] Sodium acetate<br />
[18F] NH3</td>
<td data-th="President Rong/Yang Ming">7,500</td>
<td data-th="other academic units">9,750</td>
<td data-th="industry">15,000</td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ed_model06 clearfix">
<div class="table01">
<table class="ed_table caption-top" summary="Regular Medication Prices">
<caption>Special Medication Prices</caption>
<tbody>
<tr>
<th scope="col">Special medication (times)</th>
<th scope="col">Taipei Veterans General Hospital/Yang Ming</th>
<th scope="col">other academic units</th>
<th scope="col">industry</th>
</tr>
<tr>
<td class="ed_pc_center" data-th="Special medication (times)">[11C] PIB<br />
[18F] FEPPA<br />
[18F] FAHA<br />
4-[18F] ADAM<br />
[18F] FHBG<br />
[18F] THK5351</td>
<td data-th="President Rong/Yang Ming">7,500</td>
<td data-th="other academic units">9,750</td>
<td data-th="industry">15,000</td>
</tr>
<tr>
<td class="ed_pc_center" data-th="Special medication (times)">Newly developed drugs</td>
<td data-th="President Rong/Yang Ming">15,000</td>
<td data-th="other academic units">19,500</td>
<td data-th="industry">30,000</td>
</tr>
</tbody>
</table>
<ul>
<li>The Nuclear Medicine Department of Taipei Veterans General Hospital will collect the charges for positron radiopharmaceuticals. It cannot be combined with the usage fees.</li>
<li>If there is any error or change, the announcement of the Nuclear Medicine Department of Taipei Veterans General Hospital shall be the mainstay.</li>
<li><a href="https://wd.vghtpe.gov.tw/nmed/Index.action" rel="noreferrer noopener" target="_blank" title="Website of The Nuclear Medicine Department of Taipei Veterans General Hospital(Open New Windows)">Website of The Nuclear Medicine Department of Taipei Veterans General Hospital</a></li>
</ul>
</div>
</div>Payment Method<div class="ed_model01 clearfix">
<div class="ed_txt"><strong><span style="font-size:120%;">Payment method (please follow the purchase method and order)</span></strong><br />
<strong>By Cash</strong></div>
<ol>
<li class="ed_txt">Fill out the User Consent Certificate in duplicate and ask the project host to sign or seal it.</li>
<li class="ed_txt">Bring the user consent certificate (in duplicate) to the cashier group to pay (stamp, take receipt).</li>
<li class="ed_txt">Bring the User Consent Certificate (in duplicate), payment receipt, and IACUC certificate to the Small Animal Imaging Core Facility to log in for hours.</li>
</ol>
<div class="ed_txt"><strong>By Check</strong></div>
<ol>
<li class="ed_txt">Fill out the User Consent Certificate in duplicate and ask the project host to sign or seal it.</li>
<li class="ed_txt">Bring the cheque and the user consent certificate (in duplicate) to the cashier team to pay (stamp, take the receipt).</li>
<li class="ed_txt">Bring the User Consent Certificate (in duplicate), payment receipt, and IACUC certificate to the Small Animal Imaging Core Facility to log in for hours.</li>
</ol>
<div class="ed_txt"><strong>On-Campus Loan Methods</strong></div>
<ol>
<li class="ed_txt">Fill in the user certificate in duplicate, ask the project host to sign or seal it, and fill in the school loan slip in the accounting requisition system.<br />
(Pre-loan application and write-off → payee details → beneficiary code key in "000" → NYCU internal transfer).</li>
<li class="ed_txt">Prepare documents of on-campus loan slip and user consent certificate to the Small animal imaging core facility Office - Stamped (the stamped certificate is the loan voucher).</li>
<li class="ed_txt">After completing item (2), hold the on-campus loan receipt and loan voucher (with small animal imaging core facility certificate after the office seal) to the Accounting Office to apply for the loan.</li>
<li class="ed_txt">After completing item (3), wait approximately three to four weeks for the cashier team to notify you to collect your receipt.<br />
Please prepare the following documents: the original copy of the user certificate (in duplicate) and the cashier's seal.</li>
<li class="ed_txt">Present receipt, User Consent Certificate (in duplicate) stamped by the Cashier team, and IACUC attestation to the Small animal imaging core facility to log in for hours.</li>
</ol>
</div>
<div class="ed_model17 clearfix ed_list">
<ul>
<li class="d-flex"><span style="vertical-align: inherit;"><span style="vertical-align: inherit;">Reference document for sending a letter of inter-school remittance</span> </span>
<ul class="d-flex">
<li><a href="/userfiles/ordch/files/20231016091029124.odt" rel="noreferrer noopener" target="_blank" title="Open New Windows"><img alt="Reference document for sending letter of inter-school remittance" src="/userfiles/file/odt.png" /> </a></li>
</ul>
</li>
</ul>
</div>https://www.nycu.edu.tw/ord/en/app/machine/image?module=machine&detailNo=1168438556436205568&init=YSmall animal positron and MRI instrument Bruker 7T PET MRhttps://ord.edu.tw/ord/en/app/artwebsite/view?module=artwebsite&id=2023&serno=da69be39-dc4e-48d6-9168-7c96b2dbdb6eInstrument List of YM Campushttps://www.nycu.edu.tw/ord/en/app/machine/list?module=machine&id=2038Biomedical Imaging
- <![CDATA[[YangMing] Magnetic resonance imaging core facility (3T-MRI)]]><![CDATA[<div class="ed_model05 clearfix">
<div class="ed_pic_right"><img alt="Magnetic Resonance Imaging Core Facility 3T-MRI" src="/userfiles/ordch/images/20231013164328306.jpg" /></div>
<ul>
<li class="ed_txt"><strong>Magnetic Resonance Imaging</strong>
<ul>
<li class="ed_txt">Manufacturer model: Siemens Triomagnetom a tim system</li>
</ul>
</li>
<li class="ed_txt"><strong>Instrument location: </strong>Yang-Ming Campus
<ul>
<li class="ed_txt"><strong>Room B210, Library, Information & Research Building</strong></li>
</ul>
</li>
<li class="ed_txt"><strong>Responsible person: Prof. Lin, Ching-Po </strong>
<ul>
<li class="ed_txt">Extension 67338</li>
</ul>
</li>
<li class="ed_txt"><strong>Administrator: Ms. Zhang</strong>
<ul>
<li class="ed_txt">Extension 66033</li>
<li class="ed_txt">E-mail <a href="mailto:mri.nymu@gmail.com" title="mri.nymu@gmail.com">mri.nymu@gmail.com</a></li>
</ul>
</li>
<li class="ed_txt"><strong>Term of use: See usage rules</strong></li>
<li class="ed_txt"><strong>Booking>>><a href="http://bclab.lab.nycu.edu.tw/mri_website/booking/cal/cal_login.php" rel=" noreferrer noopener" target="_blank" title=" 3T MRI Reservation System (Open a new window)"> 3T MRI Reservation System</a></strong></li>
<li class="ed_txt"><a href="http://bclab.lab.nycu.edu.tw/mri_website/mri_index.html" rel="noreferrer noopener" target="_blank" title="Magnetic Resonance Imaging Core Laboratory(Open a new window)">Magnetic Resonance Imaging Core Laboratory</a></li>
</ul>
<div class="ed_txt"> </div>
</div>]]>Instrumentation Resource Center 2025-01-15Instrument Introduction<ul>
<li class="ed_model01 clearfix">Nuclear magnetic resonance has long been a powerful physical and chemical analysis tool. Since 1980, the newly invented imaging method (magnetic resonance imaging, MRI) has been widely used in the medical field because it can observe 3D tomographic images of living bodies. In addition, MRI can be controlled appropriately to obtain images of different parameters, such as temperature, flow, water content, molecular diffusion, perfusion, chemical shift, functional MRI, and pictures of different nuclear species such as hydrogen, carbon, phosphorus, etc. It has been expanded to apply to animals, plants, materials, food technology, cognitive science, linguistics, psychology, and other humanities.</li>
<li class="ed_model01 clearfix">MRI has become an important imaging tool in clinical diagnosis in recent years. To image the internal organs of the human body with this accurate method without invading is very important for medical diagnosis, treatment, and follow-up work.</li>
<li class="ed_model01 clearfix">NMR refers to the resonance phenomenon caused by the electron nucleus being excited by electromagnetic waves in a static magnetic field, which involves specialties in the magnetic moment, spin angular momentum, lattice relaxation, pulse, and diffusion coefficient. It is difficult to understand, but if you compare it to a basin of water, it is not difficult to find that its principle is quite simple. MRI uses the principle of magnetic fields to change the rotational arrangement direction of hydrogen atoms in the body. The atomic nuclei will release the absorbed energy, and the excited energy will emit electromagnetic wave signals, which are then combined into images through computer analysis. These are the commonly seen MRI images. The principle of MRI is to place the human body in a magnetic field and change the regional magnetic field with radio wave pulses to stimulate the resonance of hydrogen nuclei in human tissues. Different human body tissues will produce different magnetic moment change signals, which are then processed by computers to present cross-sectional images of human tissue. The magnetic field strength of MRI is expressed in a magnetic unit (Tesla).</li>
<li class="ed_model01 clearfix">The human body is an organism entirely of water. The diffusion of water molecules is a random movement in three-dimensional space, and the surrounding environment will affect the movement speed. If the human body is regarded as a basin of water, the water inside will ripple in circles when the outer edge of the basin is tapped hard. At this time, if a finger is inserted into water, the original concentric ripples will be destroyed. Water molecules in the human body contain many hydrogen nuclei, which have magnetic field properties, like a small magnet. An MRI scan places the human body in a solid and uniform static magnetic field and excites hydrogen nuclei with specific frequency wave pulses in human tissues. MRI is non-invasive to the human body and does not produce ionizing radiation. It can scan in multiple directions and provide three-dimensional images with high-contrast resolution. It is an indispensable diagnostic tool for modern medicine. One of its benefits is that no matter how often it is used, it will not cause harm to the patient like traditional examination methods such as X-rays.</li>
<li class="ed_model01 clearfix">When there are abnormal tissues, the diffusion of water molecules is hindered. We can accurately distinguish normal and abnormal tissue by comparing the movement speed of water molecules detected by MRI scanning. In the early days, 70% to 80% of MRI examinations were performed on the central nervous system, such as the brain, spine, etc. MRI, which can scan at multiple angles, is a more powerful diagnostic tool compared with X-rays and computed tomography for the complex structure of the head and neck. In recent years, MRI has become increasingly widely used, not only gradually applied to the skeletal, nervous system, abdomen, and thorax, but also for angiography and cholangiography diagnosis. MRI scans can detect diseases including multiple sclerosis, long-term low back pain, malignant tumors, central nervous system infectious diseases, congenital spinal cord malformations, cardiovascular disease, neonatal metabolic diseases, degenerative diseases of the elderly, fetal images from pregnant women, brain functional images, brain micro-perfusion images, brain micro-diffusion images, three-dimensional spatial reconstruction images, hydrogen proton chemical shift images, spinal fat suppression images, cerebrospinal fluid dynamic images, sub-brain high-resolution dynamic perfusion images, abdominal diseases such as hemangioma, liver cancer and other dynamic perfusion imaging, rectal line high-resolution angiography, hepatobiliary and pancreatic angiography, cardiopulmonary angiography, breast dynamic perfusion imaging and other soft tissue lesions. Moreover, surgeons can also use MRI technology to draw a road map as a guide for surgery.</li>
<li class="ed_model01 clearfix">This technology allows doctors to obtain much information about the patient's condition before surgery. In addition to diagnosing the structure of the human body, the newly developed functional MRI examination can also observe physiological changes. For example, it can be used in the brain to explore mental functions, such as understanding the physiological abnormalities in the brains of hyperactive children and the change of brains when using different languages, etc. Some have also begun to study the combination of other examination technologies, such as MRI and computed tomography (CT), to present virtual images of the body. If the technology is skilled, virtual endoscopy can be performed.</li>
</ul>Reservation and Application Process<div class="ed_model01 clearfix">
<div class="ed_txt"><span style="font-size:110%;"><strong>Opening Hours</strong></span></div>
<ul>
<li class="ed_txt">Opening Hours: Monday to Friday from 9 am to 6 pm.</li>
<li class="ed_txt">The rest of the time will be open depending on the equipment's usage and technician's availability.</li>
</ul>
<div class="ed_txt"><strong><span style="font-size:110%;">Reservation</span> >></strong> <a href="http://bclab.lab.nycu.edu.tw/mri_website/booking/cal/cal_login.php" rel="noreferrer noopener " target="_blank" title="3T MRI Reservation System(Open a new window)">3T MRI Reservation System</a></div>
<ol>
<li class="ed_txt">Full-time NYCU faculty members can make long-term regular appointments after the research project is approved. Please refer to #11 for the specifications.</li>
<li class="ed_txt">NYCU users can make reservations six weeks in advance (42 days).</li>
<li class="ed_txt">Users from NYCU Teaching Hospital and Taiwan United University System can make reservations five weeks in advance (35 days).</li>
<li class="ed_txt">Off-campus academic units, public hospitals, and other business units can make reservations four weeks in advance (28 days).</li>
<li class="ed_txt">The system opens reservations for the next day at 00:00 every day (for example, 01/01 at 00:00 opens the reservation period for 02/11).</li>
<li class="ed_txt">All billing and payment procedures must be completed before the experiment. Otherwise, all appointments for the month will be canceled.</li>
<li class="ed_txt">If you want to cancel the experiment, please log in to the reservation system seven days before the experiment to cancel it yourself. If you cancel 3 to 6 days before the experiment, half of the reservation time will be deducted. If you cancel 1 to 2 days before the experiment, the canceled session will be charged as usual. (For example, if the reservation for 9/8 is canceled on 9/1, the hours will not be deducted; if the reservation for 9/4~7 is canceled on 9/1, half the time will be deducted. If the reservation for 9/2~3 is canceled on 9/1, the fee will be charged as usual.)</li>
<li class="ed_txt"><strong>Users should use the reservation system to reserve a time slot. For new experiments, please inform the operator of the experiment content one week before use.</strong></li>
<li class="ed_txt">Those not registered on the reservation system cannot use it.</li>
<li class="ed_txt">When the experiment exceeds the reservation time, if there are subsequent reservations from other units, the use can be extended for up to ten minutes with the consent of the next user. The user can extend the session if there are no subsequent reservations from other units. Any extension of more than twenty minutes will be charged according to the actual usage period. Any less than one hour will be counted as one hour.</li>
<li class="ed_txt">For laboratories requiring long-term regular reservations, the experiment project must be more than three months, and the reservations should be conducted for a fixed period and shall not be changed. Please contact the center administrator in advance. The Magnetic Resonance Imaging Center will try its best to accommodate you during the reserved time slot based on the situation at the time. The center will make all reservations.</li>
</ol>
<div class="ed_txt"><span style="font-size:110%;"><strong>Application process</strong></span></div>
<ol>
<li class="ed_txt">Apply for a 3T-MRI user account: Please fill in the basic application information online first (please click the link below — <a href="https://docs.google.com/forms/d/e/1FAIpQLSes_1ouU2f2nXn54towfu4YFgfZWte-c_GqHutBfyEgoFM8wg/viewform?usp=sf_link" rel="noreferrer noopener" target="_blank" title="Basic information(Open New Windows)">Basic information</a>)<br />
<strong>[Note: Users MUST complete this form "for every application" to facilitate contact and verification of payment information for each application.]</strong></li>
<li class="ed_txt">Download and complete the "NYCU Magnetic Resonance Imaging Facility Use Consent Form" and attach the Human Experiment Consent Form or Animal Experiment Consent Form.<br />
<strong>[Note: If you are applying for the first time, please fill in the user account by yourself (English, numbers, English + numbers)]</strong></li>
<li class="ed_txt">After the applicant unit receives the opinion of the instrument manager on the experimental technology, it will be sent to the instrument usage management committee on duty that month for review.</li>
<li class="ed_txt">Once approved, the relevant billing and payment process will be carried out. Please refer to the file download "NYCU Magnetic Resonance Imaging Facility Payment Instructions."</li>
<li class="ed_txt">After the payment is completed, please bring the certificate of use consent and the relevant documents specified in the payment instructions to Room813, 8th Floor, Library, Information & Research Building to apply for hours.</li>
<li class="ed_txt">Enter the reservation system to reserve a session. Please confirm the experimental order and imaging procedures with the operator before experimenting.</li>
</ol>
</div>Charges<div class="table01">
<table class="ed_table caption-top" summary="Default table format">
<caption>Charging standards (unit: NTD)</caption>
<tbody>
<tr>
<th scope="col">Users</th>
<th scope="col">Self-operation</th>
<th scope="col">Technician operation service</th>
</tr>
<tr>
<td class="ed_pc_center" data-th="user" style="text-align: left;">NYCU</td>
<td data-th="Instrument usage fee (unit: NTD)" style="text-align: center;">4,000 /hour</td>
<td data-th="Instrument usage fee (unit: NTD)" style="text-align: center;">4,500 /hour</td>
</tr>
<tr>
<td class="ed_pc_center" data-th="User" style="text-align: left;">NYCU Teaching Hospital and Taiwan United University System</td>
<td data-th="Instrument usage fee (unit: NTD)" style="text-align: center;">4,500 /hour</td>
<td data-th="Instrument usage fee (unit: NTD)" style="text-align: center;">5,000 /hour</td>
</tr>
<tr>
<td class="ed_pc_center" data-th="User" style="text-align: left;">Off-campus academic units and public hospitals</td>
<td data-th="Instrument usage fee (unit: NTD)" style="text-align: center;">Not allowed</td>
<td data-th="Instrument usage fee (unit: NTD)" style="text-align: center;">5,500 /hour</td>
</tr>
<tr>
<td class="ed_pc_center" data-th="User" style="text-align: left;">Other off-campus business units</td>
<td data-th="Instrument usage fee (unit: NTD)" style="text-align: center;">Not allowed</td>
<td data-th="Instrument usage fee (unit: NTD)" style="text-align: center;">6,500 /hour</td>
</tr>
</tbody>
</table>
</div>
<div class="ed_model06 clearfix">
<div class="ed_txt"> </div>
<ul>
<li class="ed_txt">Peak hours: Monday to Friday, 9 a.m. to 6 p.m.</li>
<li class="ed_txt">Off-peak time: Besides the above time, this period might be open depending on the instrument's usage and the technician's status.</li>
<li class="ed_txt"><strong>This instrument is operated by specialized technicians. If the applicant wants to self-operate, he/she must hold a radiologist's license, receive 40 hours of instrument operation training from the center, be approved by the examination, and have the signature and consent of the project director. After passing the certificate, they can operate the machine on their own and undergo magnetic resonance imaging training courses and tests every year to renew their operating qualifications.</strong></li>
</ul>
</div>Usage Rules<div class="ed_model01 clearfix">
<div class="ed_txt"><strong>Rules for the use of magnetic resonance imaging equipment</strong></div>
<ol>
<li class="ed_txt"><span style="color:#e74c3c;"><strong>This instrument is operated by specialized technicians. If the applicant wants to self-operate, he/she must hold a radiologist's license, receive 40 hours of instrument operation training from the center, be approved by the examination, and have the signature and consent of the project director. After passing the certificate, they can operate the machine on their own and undergo magnetic resonance imaging training courses and tests every year to renew their operating qualifications.</strong></span></li>
<li class="ed_txt">Anyone who pretends to be someone else’s certified qualification to operate an instrument will have his/her project host research reservation rights to use the instrument suspended and revoked.</li>
<li class="ed_txt">Please take good care of the instruments and related equipment and ensure that the instrument environment is clean and tidy. After each use of the core facilities, please close all items or return them to their original places (such as projectors, projectors, etc.) before leaving. Goggle equipment, public items in this core facility, etc.), and food waste should be packed away. Personal items (such as computers) on the operating table should be collected within the reservation period to avoid affecting the next user. If the user needs to borrow all the equipment or public spaces of this core facility outside of the scheduled time, please receive the consent of the operator and the user during that time period. However, this core facility will not be responsible for any situation that occurs.</li>
<li class="ed_txt">This core facility is only responsible for assisting in conducting experiments. Please follow the regulations of the Human Experimentation Committee for the safety of subjects during the research process. The MRI core facility is not responsible.</li>
<li class="ed_txt">Users are required to provide a completed Human Experimentation Committee consent form for each experiment. If there are safety concerns, the MRI core facility can cancel the experiment.</li>
<li class="ed_txt">Users are required to prepare the consent form and basic information about the subjects required for the research process by themselves. The preparation of the subjects before scanning, the description of the experimental process, and the contact with the subjects are in this core. The facility is not responsible. Each subject must fill in a Subject Examination Confirmation Form for each scan and keep it in our center. For the confirmation form file, please see "<a href="http://bclab.lab.nycu.edu.tw/mri_website/download.html" rel="noreferrer noopener" target="_blank" title="File Download(Open New Windows)">File Download</a>."</li>
<li class="ed_txt">Before entering the scanning room, users and subjects should confirm that there are no contraindications for magnetic resonance imaging on their bodies, and they can only enter with the consent of the instrument operator.</li>
<li class="ed_txt">Users must set up the equipment required for the experimental process (such as projectors, goggles equipment, etc.) by themselves.</li>
<li class="ed_txt">The charging standard for this instrument only calculates the cost of consumables and does not include instrument purchase, maintenance, etc. To avoid wasting public resources, please confirm that the experimental design is good and the conditions of the subjects are good. If the experimental results are not caused by instrument failure, users must still pay according to the charging standards.</li>
<li class="ed_txt">If the experiment cannot be completed due to poor design of the experimental process or inability to coordinate the time between the user and the subject, the user must still pay according to the charging standards.</li>
<li class="ed_txt">In the event of natural disasters such as earthquakes and typhoons during the experimental appointment period, If the Taipei City Government announces the suspension of classes or classes, this core facility will not be open all day, and all reserved hours will be returned. If there is a temporary failure of the magnetic resonance imaging scanner during the experimental appointment period, the core facility will decide whether to cancel the experiment depending on the repair situation. If the experiment is canceled, all reserved hours will be returned.</li>
<li class="ed_txt">The MRI core facility is not responsible for storing user items. If users need to store items in the public space of this core facility, they must first obtain the consent of the administrator. If the item will be stored for more than one month, please label the item with the owner's name.</li>
<li class="ed_txt">The project manager will be notified for the first time for those who do not follow the usage rules, do not shut down the machine normally, or fail to show up without any reason. The rights of reservation will be canceled for one month for the second time and will be canceled for half a year for the third time.</li>
<li class="ed_txt">Please download the experimental results within 5 days after the experiment. The hard disk, disc, and other media for storing files must be prepared by yourself. The MRI core facility is not responsible for data storage and data processing. In addition, this core facility will regularly delete all experimental results on the day of instrument maintenance, so users are advised to pay attention.</li>
<li class="ed_txt">If there are any abnormalities in the machine during the experiment, be sure to ensure the safety of the subjects and report it immediately afterwards.</li>
</ol>
<div class="ed_txt"><strong>Reward Usage Rules</strong><br />
Each full-time NYCU faculty member is entitled to three hours of free testing to test and obtain preliminary research data.<br />
<br />
<strong>Other notes</strong></div>
<ol>
<li class="ed_txt">Precautions for human experimentation (to be specified separately).</li>
<li class="ed_txt">Precautions for animal experimentation (specified separately).</li>
<li class="ed_txt">When the experimental results using this magnetic resonance imaging instrument are included in published documents, please thank this core facility in the Acknowledgment section, and please e-mail the PDF electronic file of the document to the instrument administrator.</li>
<li class="ed_txt">Acknowledgement：<br />
The authors acknowledge MR support from National Yang-Ming University, Taiwan, which is in part supported by the MOE plan for the top university.</li>
</ol>
</div>Related Links<div class="ed_model01 clearfix">
<div class="ed_txt">If the relevant content is revised and cannot be reproduced, all content will be marked as "<a href="http://bclab.lab.nycu.edu.tw/mri_website/mri_index.html" rel="noreferrer noopener" target="_blank" title="Magnetic Resonance Imaging Core Laboratory (Open a new window)">Magnetic Resonance Imaging Core Laboratory</a>" Website content is mainly.</div>
</div>Contact<div class="ed_model22 clearfix">
<div class="row w-100 mx-0">
<ul class="col-12 col-md-4">
<li class="full-name">Ms. Zhang</li>
<li class="job-title">Administrator</li>
<li class="li"><img alt="phone" src="/userfiles/editor/ic_phone.svg" /> 02-28267000 #66033</li>
<li class="li"><img alt="mail" src="/userfiles/editor/ic_mail.svg" /> <a href="mailto:mri.nymu@gmail.com" title="mri.nymu@gmail.com">mri.nymu@gmail.com</a><span style="vertical-align: inherit;"><span style="vertical-align: inherit;"> </span> </span></li>
</ul>
</div>
</div>
<div class="ed_model22 clearfix">
<div class="ed_model22 clearfix">
<div class="row w-100 mx-0">
<ul class="col-12 col-md-4">
<li class="full-name">Ms. Chi</li>
<li class="job-title">Assistant</li>
<li class="li"><img alt="phone" src="/userfiles/editor/ic_phone.svg" /> 02-28267000 #66129</li>
<li class="li"><img alt="mail" src="/userfiles/editor/ic_mail.svg" /> <a href="mailto:evonne2170@gmail.com" title="evonne2170@gmail.com">evonne2170@gmail.com</a><span style="vertical-align: inherit;"><span style="vertical-align: inherit;"> </span> </span></li>
</ul>
</div>
</div>
</div>
<div class="ed_model22 clearfix">
<div class="ed_model22 clearfix">
<div class="row w-100 mx-0">
<ul class="col-12 col-md-4">
<li class="full-name">Professor Lin Ching-po</li>
<li class="job-title">Responsible person</li>
<li class="li"><img alt="phone" src="/userfiles/editor/ic_phone.svg" /> 02-28267338</li>
<li class="li"><img alt="mail" src="/userfiles/editor/ic_mail.svg" /> <a href="mailto:cplin@ym.edu.tw" title="cplin@ym.edu.tw">cplin@ym.edu.tw</a><span style="vertical-align: inherit;"><span style="vertical-align: inherit;"> </span> </span></li>
</ul>
</div>
</div>
</div>https://www.nycu.edu.tw/ord/en/app/machine/doc?module=machine&detailNo=1168789333474283520&type=sNYCU MRI Core Facility - Health Declarationhttps://www.nycu.edu.tw/ord/en/app/machine/doc?module=machine&detailNo=1168789333537198080&type=sNYCU MRI Core Facility - Payment Instructionshttps://www.nycu.edu.tw/ord/en/app/machine/doc?module=machine&detailNo=1168789333562363904&type=sNYCU MRI Core Facility - Reference Document for Inter-campus Remittance Lettershttps://www.nycu.edu.tw/ord/en/app/machine/doc?module=machine&detailNo=1168789333583335424&type=sNYCU EEG system borrowing regulationshttps://www.nycu.edu.tw/ord/en/app/machine/doc?module=machine&detailNo=1168789333604306944&type=sNYCU MRI Center - Subject Examination Confirmation Formhttps://www.nycu.edu.tw/ord/en/app/machine/doc?module=machine&detailNo=1168789333625278464&type=sNYCU MRI Core Facility - Certificate of consent for usehttps://www.nycu.edu.tw/ord/en/app/machine/image?module=machine&detailNo=1168785805406113792&init=YMagnetic resonance imaging core facility (3T-MRI)https://ord.edu.tw/ord/en/app/artwebsite/view?module=artwebsite&id=2023&serno=da69be39-dc4e-48d6-9168-7c96b2dbdb6eInstrument List of YM Campushttps://www.nycu.edu.tw/ord/en/app/machine/list?module=machine&id=2038Biomedical Imaging