NYCU Instrumentation Resource Center Management Regulations National Yang Ming Chiao Tung University Instrumentation Resource Center Management Regulations Approved at the 5th Administrative Meeting of the 2021 Academic Year on February 18, 2022 Revised and approved at the 2nd Administrative Meeting of the 2022 Academic Year on October 26, 2022 Revised and approved at the 4th Administrative Meeting of the 2024 Academic Year on February 19, 2025 Chapter 1. Purpose of Establishment Article 1. National Yang Ming Chiao Tung University (hereinafter referred to as NYCU) has established these regulations to implement the National Science and Technology Council (NSTC) subsidized Common Use Service Project for Basic Research Core Facilities (hereinafter referred to as the NSTC Basic Research Core Facilities Service Project). These regulations are formulated to achieve the following tasks: to encourage the open service of the self-purchased instruments for internal and external research units; to strengthen the usage of instrument resources and service quality; to effectively perform the tasks of centralized instrument procurement, utilization, management, and maintenance; to improve the efficiency of instrument use; to enhance the standard of academic research. Article 2. The Instrumentation Resource Center of NYCU (hereinafter referred to as the Center) is affiliated with the Office of Research and Development of NYCU. In response to the management conditions of the instruments located on different campuses, there is a “Review Committee” and a “Users’ Committee.” I. “The Review Committee” is mainly responsible for reviewing matters related to the Basic Research Core Facility (BRCF) of the National Science and Technology Council (NSTC). The Dean of Research and Development is the chairperson. The Dean of Research and Development, the Director of the Center, and the Review Committee members of the Basic Research Core Facility Developmental Program are the ex-officio members. In addition, ten faculty members with experience in instrument management from those Colleges of related instrument use shall be appointed for a two-year term with the approval of the Dean of Research and Development. Half of the appointed committee members shall be re-selected every year. Members are eligible for re-election. II. The “Users’ Committee” consists of 11 to 15 members and is mainly responsible for supervising and inspecting matters related to common instruments. The Dean of Research and Development (the chairperson) is an ex-officio member. The rest of the committee comprises faculty members who are assistant professors or above, recommended by those colleges of related instrument use and the Office of Research and Development of NYCU. Each unit can recommend a maximum of three faculties members. The Dean of Research and Development shall appoint these candidates and select several alternate members. The vacancies on the committee will be filled in order by the alternate list. The committee members are elected for a two-year term, based on the academic year, and are eligible for re-election. Those who serve as committee members due to their positions will be promoted and retired according to their duties. Article 3. The operation and management of the basic research core facilities of NYCU are divided into five major fields: nanotechnology, materials, applied chemistry, physics, and biotechnology. To effectively improve the service performance and management of instrument technicians, the management units of each basic research core facility are integrated according to their fields and establish the “Management Committee” and elect a chairperson to participate in the “coordination meeting” of the Center. Each management committee shall formulate its rules and regulations and submit them to the Center for approval before implementation. Chapter 2. The Basic Research Core Facility Article 4. Inclusion and withdrawal of instruments I. The basic research core facilities of the center only include the instruments participating in the Basic Research Core Facilities Service Project of the National Science and Technology Council (NSTC). Applications for the inclusion of instruments in the service project shall follow the regulations of NSTC, be approved by the Management Committee of its field, and be submitted to the “Review Committee” of the Center for review and approval. The Center shall apply to NSTC, and the Director of the Center shall be the primary project coordinator. II. For instruments with poor long-term service performance, the “Review Committee” of the Center shall deliberate whether to apply to NSTC for withdrawal from the service project. Article 5. Personnel Management I. The Center and the management units of each basic research core facility may hire technicians and administrative assistants to ensure the proper operation and maintenance of the instruments and handle administrative tasks. The duration of employment for these personnel will be aligned with the implementation period of the NSTC basic research core facility service project, unless specified otherwise. II. The salary of the personnel subsidized by NSTC’s basic research core facility service project is based on the standard salary scale set by the University for the full-time project staff, and the management of the personnel is under the relevant regulations of NYCU and NSTC. The salaries of personnel employed by the management units with other funds are in accordance with the relevant regulations of the funding sources. Article 6. Operation and Management of Funds I. The service fees of basic research core facilities shall be charged in accordance with the regulations of NSTC. The revenue from services scheduled by academic and research units within/out of NYCU with NSTC projects is exempted from the University's management fee. After deducting the monthly National Science and Technology Development Fund, 20% of the remaining revenue from services not scheduled by NSTC projects is set aside as NYCU’s management fee. II. Service fees collected by the Center will be allocated to the National Science and Technology Development Fund of NSTC and the management fee of the University. The rest will be dedicated funds and be reimbursed for actual expenses by the management units of the basic research core facilities after the deduction of the Center’s coordination fund. A single expenditure for 100,000 NTD or more of the Center’s coordination fund must be approved by the “Review Committee.” III. In addition to the subsidies and service income from the NSTC’s basic research core facility service project, the maintenance fee, the salary of full-time or part-time technicians and administrative assistants, and the consultant fee of instrument experts shall be financed by each basic research core facility management unit when necessary. IV. The Center's project and service revenue expenses are governed by the NSTC’s “Consent for the Implementation of the Basic Research Core Facility Common Use Service Project.” Article7. Operation and Management of Instruments I. The operation and management guidelines for the Center’s basic research core facilities shall be determined and approved by the Management Committee of each field. These shall be submitted to the Center for records, and the same applies to amendments. II. Each basic research core facility of the Center shall have an instrument expert to provide professional management and consulting services. Instrument experts shall supervise the instrument's regular operation and the technicians' performance. The appointment of at least one instrument expert shall be submitted by the Management Committee of each field to the “Review Committee” for deliberation and resolution before implementing each annual project. Chapter 3. Common Instruments Article 8. Establishment of the common instruments I. The Center shall arrange and procure instruments and equipment with high commonality for shared use by students and faculty both on and off campus. II. Instruments and equipment that exceed three million NTD in value may be applied to join the operation of common instruments by an on-campus unit or individual. Article 9. Management of the common instruments I. Each common instrument shall establish a webpage to promote the instrument and publicize the service hours. Respective charging standards for each common instrument shall be formulated to collect usage fees during service hours. II. The information on education and training courses, users’ qualification certification, dedicated operation services, instrument reservation, etc., shall be published on the website for users’ inquiry and utilization. III. There shall be special accounts for service revenues. Each common instrument management unit shall be reimbursed with receipts for actual expenses. The financial operation of each management unit shall be self-sufficient. Expenses from the special account for common instruments shall be restricted to the payment of personnel costs, equipment costs, and operating expenses related to common instruments. Shall not be used for other purposes. IV. The service revenue of each common instrument management unit shall be transferred to the Center’s special account of common instruments for dedicated purposes after deducting 20% of the management fee from NYCU. However, the service revenue gained from the faculty and students of NYCU, National Central University, National Chengchi University, and National Tsing Hua University shall be exempted from the management fee payable to NYCU. V. The “Review Committee” or the “Users’ Committee” will deliberate the withdrawal from the operation of common instruments. VI. The regulations on the open use of common instruments, the management of external escrowed instruments, the various fee regulations, and the grant proposal procedures are in accordance with other relevant rules of the Centre. Chapter 4. Supplementary Provisions Article 10. This regulation shall be implemented after approval by the Administrative Meeting. The same applies to amendments.

[NSTC Basic Research Core Facility] Operation and Management Regulations Article 1- PURPOSE The purpose of these Operation And Management Regulations is to strengthen the performance of the Instrumentation Resource Center of National Yang Ming Chiao Tung University (hereinafter referred to as the Center), to properly utilize the funding and human resources of the National Science and Technology Council (hereinafter referred to as NSTC) core facilities for basic research, and to improve the efficiency of instrument use

[Common Instrument] Higher Education SPROUT Project Grant for NYCU Instrument Funding The Purpose of these guidelines is for National Yang Ming Chiao Tung University (NYCU) to effectively utilize equipment funds, establish a resource sharing platform for the Chiao Tung campus (formerly National Chiao Tung University), improve equipment specifications, and refine research performance. 2. A Full-time faculty member who has been subsidized at least NTD$3 million of equipment grants for a single instrument from a single external project, or more than NTD$5 million of equipment grants for a cluster of instruments from external projects, may apply for a subsidy from the Instrumentation Resource Center of the Office of Research and Development when there is a shortfall in funding. The approved list of research grants is required for application. The proposal will be reviewed by the Review Committee for approval. The maximum amount of the subsidy shall be 50% of the shortfall, and NTD$3 million at most. 3. Colleges, departments, institutes, and research centers using self-raised fund (not external project grants) to acquire the equipment with listing price over NTD$3 million for a single instrument, or over NTD$5 million for a cluster of instruments, may apply for subsidies from the Instrumentation Resource Center of the Office of Research and Development when there is a shortfall in funding. The proposal will be reviewed by the Review Committee for approval. The maximum amount of subsidy shall be 50% of the self-financing amount, and NTD$3 million at most. 4. Only one application for the same equipment can be made in accordance with either the second or the third point of this regulation. 5. In the case of a cross-campus proposal, the proposed equipment shall be limited to those with general necessity across campuses. 6. The same source of funding shall be used in the principle of no duplication of subsidies. Applications that already have self-funding from Higher Education SPROUT Project shall not be accepted. 7. The committee will consider the following conditions to make the decision: (1) The proposed equipment is suitable for open use. (2) The proposed equipment can improve the research performance of the university. (3) The proposed equipment is an advanced and valuable instrument. 8. The subsidized equipment shall be incorporated into the common instrument management of the Instrumentation Resource Center in no later than two years from the date of acceptance, and services shall be provided in accordance with relevant regulations. 9. The subsidized funds shall be used with priority and within the specified period. 10. These guidelines shall be approved by the Review Committee and implemented after being approved by the President, and the same applies to amendments.

[Common Instrument] Annual Common Instrument Procurement Grant Proposal Regulations National Yang Ming Chiao Tung University Instrumentation Resource Center Yang Ming Campus Annual Common Instrument Procurement Grant Proposal Regulations Approved by the President on October 2, 2023 Article 1: Preamble The Instrumentation Resource Center (IRC) has established these regulations to ensure that common instrument facilities and service operations are compatible with the demands and future development of the entire university. Article 2: Description I. The annual instrument procurement grant proposals are divided into three categories: obsolescence, additional procurement (including expansion and upgrade of existing instruments), and new procurement. II. The proposed instruments should conform to the directions of public utility, foresight, and practicality. III. The subsidized funds must be utilized within the prescribed period. IV. If a faculty member applies for the grant, the procured instrument may be placed in the Common Facility Room of IRC. If the faculty member self-manages it, it should be included in the common facilities of IRC and established under the external escrowed instruments following the " External Escrowed Instrument Management Essentials of National Yang Ming Chiao Tung University Instrumentation Resource Center.” The subsidized applicant shall be the manager of the device. The manager shall be responsible for the management and maintenance. Besides, the committee shall formulate the regulations of instrument operation and management. Article 3: Qualification of Proposal I. The total value of the proposal must be at least NT$3 million (inclusive). II. Subsidy for instrument procurement shall be based on partial subsidies. Applicants must raise at least 20% of their funds for the instrument procurement. Applicants may apply for a grant subsidy to the Instrumentation Resource Center of the Office of Research and Development. The grant proposal shall be submitted to the Users’ Committee for review and to the President for approval. The maximum amount of subsidy depends on the annual budget of the Office of Research and III. All full-time assistant professors or assistant research fellows of NYCU or above may submit proposals, with the principle that each person may propose only one instrument per year. IV. In the case of a cross-campus proposal, the proposed instrument shall be limited to those with general necessity across campuses. Article 4: Review of Proposal I. The Instrument Resource Center shall issue an official document to notify all departments that they may submit proposals. The center will convene a review meeting according to the budget and decide on the subsidy items and amounts for the common instrument procurement. II. The Users’ Committee may invite the applicant to attend the review meeting to present. Article 5: For instruments with a proposal amount of $10 million or more, and the amount of the proposal is insufficient after deducting the number of funds prepared by the applicant and the amount of the subsidy received from IRC, the applicant may request approval from the President to subsidize the insufficient amount on a project basis. Article 6: If there is a balance in the common instrument procurement subsidy for the year, IRC may coordinate the excess funds. Article 7: This regulation shall be discussed by the Users’ Committee and implemented after approval by the President. The same applies to amendments.

[Common Instrument] YM Campus Common Instrument Operation Management Regulation Article 1. Purpose. These management regulations are formulated to promote the sound development of the Instrumentation Resource Center (IRC) and provides complete services for using common instruments to improve the research level of the University. Article 2. Opening hours and targets. Article 3. Registration of the “Access Control and Booking System of YM Campus” Article 4. Notices on the Use of Common Instruments and Reservation Regulations. Article 5. Regulations for indemnity of equipment damages due to improper use and violations of common instruments usage. Article 6. Payment Regulations for instrument usage fees. Article 7. Management Regulations for transferring various types of instruments to IRC Article 8. These regulations shall be approved by the Instrumentation Resource Center Users’ Committee and submitted to the Research and Development Office for approval before implementation. The same applies to amendments.

[Common Instrument] YM Campus Instrument Fees Regulations National Yang Ming Chiao Tung University Instrumentation Resource Center Yang Ming Campus Instrument Fees Regulations Approved by the Instrumentation Resource Center Users’ Committee Meeting on April 22, 2025. I. Flow Cytometry Fees: Charges are calculated on a half-hourly basis. A. Sorter: SRT 1. Commissioned service User Startup Fee Operation Fee NYCU faculty and students NT$ 1,000 NT$ 800/hour Educational Cooperation Organizations NT$ 1,500 NT$ 1,200/hour Other external organizations NT$ 2,000 NT$ 1,600/hour 2. Self-operating [Users are required to be certified by the administrator before use.] User Startup Fee Operation Fee Only for NYCU faculty and students Free NT$ 600/hour B. Sorter: FACSMelody 1. Commissioned service User Startup Fee Operation Fee NYCU faculty and students NT$ 1,000 NT$ 800/hour Educational Cooperation Organizations NT$ 1,500 NT$ 1,200/hour Other external organizations NT$ 2,000 NT$ 1,600/hour 2. Self-operating [Users are required to be certified by the administrator before use.] User Startup Fee Operation Fee Only for NYCU faculty and students Free NT$ 600/hour C. Analyzer: 1. FACSCalibur NYCU faculty and students Non-NYCU Users NT$ 420/hour NT$ 840/hour 2. CytoFLEX NYCU faculty and students Non-NYCU Users NT$ 280/hour NT$ 560/hour II. Imaging Core Microscope Fees: Charges are calculated on a half-hourly basis. Model NYCU faculty and students 1 Educational Cooperation Organizations 2 Other external organizations Confocal Microscope Olympus FV1000 NT$ 500/hour NT$ 750/hour NT$ 1,000/hour Olympus Fv10i NT$ 300/hour NT$ 450/hour NT$ 600/hour Zeiss LSM900 (Zeiss LSM700+) NT$ 600/hour NT$ 900/hour NT$ 1,200/hour Zeiss LSM7MP NT$ 1,000/hour NT$ 1,500/hour NT$ 2,000/hour Translated in May. 2025. Zeiss LSM880 with Airyscan (Day) NT$ 900/hour NT$ 1,350/hour NT$ 1,800/hour (Night) NT$ 500/hour Zeiss LSM900 with Airyscan 2 (Day) NT$ 800/hour NT$ 1,200/hour NT$ 1,600/hour (Night) NT$ 600/hour Fluorescent Microscope Olympus BX61 Olympus BX63 Leica DM6000B Free NT$ 50/hour NT$ 100/hour Olympus IX83 NT$ 100/hour NT$ 150/hour NT$ 200/hour Zeiss LSM880 NT$ 300/hour NT$ 450/hour NT$ 600/hour Zeiss LSM900 Zeiss Axioscan 7 NT$ 300/hour NT$ 450/hour NT$ 600/hour Advanced Microscope Zeiss Elyra 7 NT$ 1,300/hour NT$ 1,950/hour NT$ 2,600/hour III. Electron Microscope Fees: For electronic microscopes and related equipment, respective users shall cover maintenance and material consumption. The fees are as follows. A. TEM (JEOL JEM-1400plus) Operation Fee: NT$ 1,050/hour; (NT$ 2,100/hour for non- NYCU users.) B. TEM (JEOL JEM-1400plus) with EDS Operation Fee: NT$ 1,250/hour; (NT$ 2,500/hour for non-NYCU users.) C. 3D Tomography Fee: NT$ 1,050/hour; (NT$ 2,100/hour for non-NYCU users). No fee for image reconstruction analysis, while the fee may be determined depending on the usage through the committee meeting. D. SEM (JEOL JSM-7600F) Operation Fee: NT$ 600/hour; (NT$1,200/hour for non-NYCU users.) E. The operation time of less than an hour will be charged as one hour. If the user does not cancel the reservation in advance or fails to present on the scheduled day, the user shall pay the fee for the first hour of the operation. F. Ultra-thin section for TEM Specimens: NT$ 3,000 per specimen for NYCU Faculty Research Programs. (4 copper grids per specimen, staining is not included.) G. Using ultra-thin microtome: Please prepare your own glass strips for making glass cutters, or it is NT$ 360 per glass strip. H. Critical Point Drying Operation Fee: NT$ 100 per session (100% alcohol is required, excluding conductive liquid silver fee.) I. SEM specimen with gold plating: NT$ 580 per session (excluding conductive liquid silver fee). J. SEM specimen with platinum plating: NT$ 530 per session (excluding conductive liquid silver fee). K. Conductive liquid silver fee: NT$10 for each specimen on the carrier. L. SEM specimen carrier: 25 mm/NT$ 120 each, 12 mm/NT$ 60 each, 10 mm/NT$ 40 each. IV. Magnetic resonance imaging core facilities (MRI) Operation Fees: User Unit For peak hours For off-peak hours Translated in May. 2025. (technician/self-operated*) (technician/self-operated*) NYCU NT$ 4,000/$3,500* NT$ 3,500/3,000* NYCU Teaching Hospital and University System of Taiwan NT$ 4,500 NT$ 4,000 Non-NYCU academic organizations and public hospitals NT$ 5,000 NT$ 4,500 Non-NYCU Business Unit NT$ 6,000 NT$ 6,000 Peak hours: Monday through Friday, from 9:00 a.m. to 6:00 p.m. Off-peak hours: In addition to peak hours, the time slots will be open for use depending on instrument usage and operator status. V. 400 MHz Nuclear Magnetic Resonance Instrument Fees: User Rush hour (by technician / Self-operated) Off-peak time (by technician / Self-operated) NYCU NT$ 200/half an hour NT$ 200/hour Notes: 1. Rush hours: Monday to Friday, from 09:00 am to 10:00 pm. The usage time is calculated in half-hour units, and usage less than half an hour will be charged as half an hour. 2. Off-peak time: Monday to Friday, from 10:00 pm to 08:00 am of the next day, and all day on weekends. The usage time is calculated in 1-hour units, and usage less than 1 hour will be charged as 1 hour. 3. If the user cannot use it for any reason and does not cancel the reservation a day before, the user shall pay the fee for the whole reserved session. Commissioned Services 1D proton spectrum 1D carbon spectrum and other experiments Non-NYCU NT$ 350/half an hour/sample NT$ 650/hour/sample VI. Automated Clinical Chemistry Analyzer Fee: The instrument adopts a single tube charge, NT$ 50 for each tube. VII. Raman Spectrometer Operation Fees: User Status Companies and non-NYCU students NYCU Fees NT$ 1,500/hour NT$ 400/hour Note: The operation fee is NT$ 200 per hour for those who are certified to operate the Raman Spectrometer on their own. VIII. Mass Spectrometer Facilities Fees: A. Metabolomics analysis Category Service/Model Used NYCU faculty and students Educational cooperation organizations Other external organizations Translated in May. 2025. Technician operation Pre-processing of Metabolite samples NT$ 500 /pc NT$ 750 /pc NT$ 1,000 /pc All models and analysis modes will be charged at the same rate. NT$ 3,000 /pc NT$ 4,500 /pc NT$ 6,000 /pc Startup Fee (for CE-QToF) NT$ 2,000 NT$ 3,000 NT$ 4,000 Metabolite Analysis Report NT$ 500 per copy NT$ 750 per copy NT$ 1,000 per copy Self-operated Mass Spectrometer Standard Samples NT$ 500 /pc NT$ 750 /pc NT$ 1,000 /pc UPLC-QToF (WATERS XEVO QToF + ACQUITY UPLC) NT$ 1,000 /hour NT$ 1,500 /hour NT$ 2,000 /hour CE-QToF (SCIEX CESI8000 + Waters QTOF G2-XS) TQD (WATERS ACQUITY UPLC + XEVO TQD) NT$ 800/hour NT$ 1,200 /hour NT$ 1,600 /hour GC-MS (Agilent GC QqQ) CE alone NT$ 500/hour NT$ 750/hour NT$ 1,000 /hour Note: 1. We have a standardized pre-processing treatment. If applicants require specific pre- processing steps, the fee shall be discussed separately in advance. 2. The technician’s operating fee is charged based on the number of samples. All models and analysis modes are charged at the same rate. Each sample will be analyzed in triplicate. The sample loading schedule will be arranged according to the order of sample collection at the center. 3. Self-operation is charged on an hourly basis. The operation time of less than an hour will be charged as one hour. The operation time includes the time for system preparation, instrument setup, sample analysis, washing between samples, and cleaning the system after analysis. (Users require certification.) B. Proteomics analysis: technician operation only Category Service items NYCU faculty and students Educational cooperation organizations Other external organizations Technician operation Protein sample pre-processing NT$ 600/pc NT$ 900/pc NT$ 1,200 /pc Protein identification report NT$ 1,200 per copy NT$ 1,800 per copy NT$ 2,400 per copy Protein post-translation modification identification report NT$ 20,000 per copy NT$ 30,000 per copy NT$ 40,000 per copy C. Discount Plan Translated in May. 2025. To promote the utilization of the mass spectrometers, a rebate will be offered if the usage amount of the mass spectrometer facility-related services reaches a certain threshold, as shown in the table below. The usage amount of the current year will be counted in December each year and cannot be accumulated across years. The rebate will be credited against the usage fee. It is limited to the services provided by the mass spectrometer facility. The rebate is valid for an unlimited period; however, it shall not be transferred, cash discounted, or redistributed to other users. Accumulated usage amount (NT$) Rebate amount (NT$) 150,000 15,000 300,000 60,000 600,000 150,000 1,000,000 300,000 IX. Linear-Torsion All-Electric Dynamic Test Instrument Fees: A. ElectroPuls™ E10000 NYCU faculty and students Educational cooperation organizations (including academic units) Other external organizations Machine usage fee NT$ 2,000/day NT$ 250/hour NT$ 4,000/day NT$ 500/hour NT$ 8,000/day NT$ 1,000/hour Consultation fee (first-time usage) NT$ 2,000/time NT$ 2,500/time NT$ 3,000/time Fixture Rental NT$ 5,000/time NT$ 5,000/time NT$ 5,000/time New fixture design and manufacturing fees Additional fee by case Additional fee by case Additional fee by case B. ElectroPuls™ E3000 NYCU faculty and students Other external organizations Machine usage fee NT$ 8,000/day NT$ 800/hour NT$ 16,000/day NT$ 1,600/hour Consultation fee (first-time usage) NT$ 2,000/time NT$ 2,000/time Fixture Rental NT$ 5,000/time NT$ 5,000/time New fixture design and manufacturing fees Additional fee by case Additional fee by case X. Cabinet X-ray Irradiator NYCU Faculty and Students Cooperative Educational Units (Including Academic Units) Other Non-NYCU Units Machine Usage Fee NT$100 /15 minutes NT$150 /15 minutes NT$200 /15 minutes Operator’s Fee NT$200 /hour NT$200 /hour NT$200 /hour Mouse Fixator and Lead Shield Rental NT$50 /set Return on the Same Day NT$50 /set Return on the Same Day NT$100 /set Return on the Same Day Translated in May. 2025. Usage Hours Calculation 1. Machine usage fee: If the usage is less than 15 minutes, it will be counted as 15 minutes. 2. Operator’s fee: Usage of less than 1 hour will be counted as 1 hour. 3. If you want to use the machine on a Saturday, Sunday, or national holiday, and the operator is not qualified to operate the machine, the operator fee will be charged. As it is necessary to assign staff to monitor and assist in the operation of the equipment, an additional overtime charge of $1,000/day will be added, and the flexible rate can be discussed during the consultation. XI. Dry Ice Fee: A. NT$ 30 per pound. B. IRC shall charge the usage fee every two months. The payment notice will be mailed to each user in the first half of every odd month. C. A 5% additional late payment fee will be charged for every 5 days of overdue payment. (You must first contact the IRC office to verify the amount of the late payment and then go to the Cashier’s Office for payment. D. If the payment is more than three times overdue, IRC will no longer supply dry ice to the lab. XII. List of Common Instruments Fees (Currency: NT$.) # Instrument Brand/Model NYCU faculty and students １ Educational Cooperation Organizations 2 Other external organizations Description 1 Ultracentrifuge Beckman 0 200 400 Within 6 hours each time 2 Tabletop Ultracentrifuge Beckman 0 150 300 Within 6 hours each time 3 High-Speed Centrifuge Beckman 0 50 100 Within 1 hour each time 4 High Performance Vacuum Centrifuge (SpeedVac) Thermo 0 50 100 Within 4 hours each time 5 Freeze Dryer VIRTIS LABCONCO CryoDry 0 100 200 Within 3 days each time 6 ELISA Reader Tecan 0 50 100 Within half an hour each time 7 Multimode microplate reader Tecan Thermo 0 50 100 Within half an hour each time 8 UV/VIS Spectrophotometer Beckman Biochrom 0 50 100 Within half an hour each time 9 NanoDrop Spectrophotometer Thermo 0 50 100 Within half an hour each time 10 Image Scanning Densitometer GE Microtek 0 100 200 Within 1 hour each time 11 Luminescence/Fluorescen ce Imaging System Fuji GE eBLOT 0 100 200 Within 1 hour each time Translated in May. 2025. # Instrument Brand/Model NYCU faculty and students １ Educational Cooperation Organizations 2 Other external organizations Description 12 Continuous High Pressure Cell Disrupter Constant 0 50 100 Within 1 hour each time 13 Bead Beating Grinder and Lysis System MP Biomedicals 0 75 100 Within 1 hour each time 14 Cryostat Microtome Leica espredia (Thermo) 0 200 400 Within 4 hours each time 15 Automated Clinical Chemistry Analyzer Fuji 0 50 100 Within half an hour each time 16 Seahorse XFe24 Extracellular Flux Analyzer Seahorse 250 375 500 Within 4 hours each time 17 Real-Time PCR ThermoFisher BIO-RAD 0 150 300 Within 4 hours each time 18 X-Ray Film Processor Kodak 0 10 20 Per film 19 Lab-grade Water System Millipore Elga 0 15 30 per liter 20 Reagent-grade Water System Millipore Elga 0 20 40 per liter Remarks: 1. Users with the following qualifications shall be charged the same fee as “NYCU faculty and students.” (1) Branch campuses (2) Joint appointment faculty (3) National Yang Ming Chiao Tung University Hospital (4) Collaboration with NYCU, and the project/grant is under the control of NYCU 2. Users with the following qualifications shall be charged the same fee as “Educational Cooperation Organizations.” (1) Adjunct faculty (2) Teaching hospitals (Veterans General Hospital, Taipei City Hospital, Far Eastern Memorial Hospital, Cheng Hsin General Hospital, etc.) (3) University System of Taiwan (4) Companies at the Center for Industry-Academia Collaboration, NYCU.

[Common Instrument] External Escrowed Instrument Management Essentials External Escrowed Instrument Management Essentials of National Yang Ming Chiao Tung University Instrumentation Resource Center Approved by the Instrumentation Resource Center Users’ Committee Meeting on March 25, 2024 Revised and approved by the Instrumentation Resource Center Users’ Committee Meeting on April 22, 2025 I. These management essentials have been formulated to effectively manage the Center’s external escrowed instruments and enhance service performance. II. The external escrowed instruments under these management essentials refer to those with public utility, foresight, and practicality, and to those that fit the following criteria: A. The instrument is approved by the Annual Common Instrument Procurement Grant Proposal and is self-managed by the applicant faculty member. B. The university grants and subsidizes the instrument procurement through special approval, and the instrument is self-managed by the purchase unit. III. The management unit of the external escrowed instruments (from now on referred to as the escrow unit) shall formulate the essentials of the instrument management team and submit them to the Instrumentation Resource Center Users’ Committee (hereinafter referred to as the Users’ Committee) of the University for approval, so as to establish the mechanism of instrument management. IV. The Composition and Duties of the External Escrowed Instrument Management Team (referred to as the Management Team): A. The composition of the Management Team: 1. The Director of the Instrumentation Resource Centre and the previous Convenor shall be ex-officio members. The Convenor shall be elected by all members of the Management Team. The other members shall be invited by the escrow unit to form a management team with 5 or more faculty members who have experience in the use of the instrument, and the team members must include more than two colleges. 2. The term of office of the Management Team members shall be three years, and the members are eligible for re-election. Those who serve as team members due to their positions shall be appointed and removed according to their duties. The list of the Management Team members shall be submitted by the escrow unit to the Instrumentation Resource Centre for future reference. 3. The proportion of the number of team members from the escrow unit to the total number of team members shall not be more than 50%. After the adoption of this regulation, it will be applied retroactively to the escrow units applying for the instrument procurement grant since 7 September 2023. B. The Duties of the Committee: 1. To assist in the management and supervision of the instrument operation. 2. To formulate the management and charging regulations for open access and submit them to the Users' Committee Meeting of the Instrumentation Resource Center for future reference. 3. To regularly submit the usage records of the escrowed instruments to the Instrument Resource Center by the 15th day of the following month after the end of each quarter for future reference. 4. To cooperate with other important matters related to the NYCU Instrumentation Resource Center. V. The escrow unit may prioritize using the instruments following the proportion of self-financing; however, users still have to pay the usage fee. VI. The Instrumentation Resource Center may audit the income and expenses of each escrowed instrument on demand, and each escrow unit shall cooperate in providing relevant information.. VII. These essentials shall be approved by the Users' Committee of the Instrumentation Resource Center. The same applies to the amendment.